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Ritopar tablets are used to treat premature labour that has not developed complications.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
By intravenous infusion: initially 50 mcg/minute, increased gradually according to response by 50 mcg/minute every 10 minutes until contractions stop or maternal heart rate reaches 140 beats/minute; continued for 12 to 48 hours after contractions cease (usual rate 150 to 350 mcg/minute); maximum rate 350 mcg/minute. By intramuscular injection: 10 mg every 3 to 8 hours, continued for 12 to 48 hours after contractions have ceased; then switched to oral treatment. Oral maintenance treatment: one tablet (10 mg) may be given approximately 30 minutes before stopping intravenous therapy, repeated every 2 hours for 24 hours, followed by 10 to 20 mg every 4 to 6 hours; maximum oral dose 120 mg daily.
Side Effects
The common side effects of Ritopar include nausea, vomiting, flushing, sweating, tremor, low blood potassium, fast heartbeat, palpitations, and low blood pressure (patients should stay in a left lateral position throughout infusion to reduce this risk), along with uterine bleeding, fluid in the lungs, chest pain or tightness, irregular heartbeat, and swelling of the salivary glands. Prolonged use over several weeks may cause a drop in white blood cells, agranulocytosis, and liver problems such as raised transaminases and hepatitis.
Cautions & Contraindications
Warnings & Precautions
Ritopar should be used with caution in patients with suspected heart disease, high blood pressure, an overactive thyroid, low blood potassium, diabetes, or mild to moderate preeclampsia. While on this medicine, blood pressure and pulse rate should be monitored, and excessive fluid intake should be avoided.
Contraindications
Contraindicated in patients known to be hypersensitive to ritodrine hydrochloride or to any of the excipients in this preparation. As a β2-agonist, ritodrine should not be used in women with cardiac disease or with significant risk factors for myocardial ischaemia. It should also be avoided in the presence of antepartum haemorrhage, intra-uterine infection, intra-uterine fetal death, placenta praevia, abruptio placentae, threatened miscarriage, cord compression, or eclampsia and severe pre-eclampsia.