Save on this medicine
Other brands with the same active ingredient
These brands contain the same active ingredient (Tinidazole). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Proticid is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Prevention of postoperative infections: adults take a single oral dose of 2 g about 12 hours before surgery. For children under 12 years, there are not enough data to recommend a dose for preventing anaerobic infections. Trichomoniasis: a single 2 g oral dose taken with food. Sexual partners should be treated with the same dose at the same time. Giardiasis: adults take a single 2 g dose with food. Children older than three years take a single dose of 50 mg/kg (up to 2 g) with food. Intestinal amebiasis: adults take 2 g per day for 3 days with food. Children older than three years take 50 mg/kg per day (up to 2 g per day) for 3 days with food. Amebic liver abscess: adults take 2 g per day for 3 to 5 days with food. Children older than three years take 50 mg/kg per day (up to 2 g per day) for 3 to 5 days with food. Bacterial vaginosis: non-pregnant adult women take 2 g once daily for 2 days with food, or 1 g once daily for 5 days with food. This medicine should be taken with food, during or immediately after meals.
Side Effects
Reported side effects have generally been infrequent, mild and self-limiting. Gastrointestinal side effects include nausea, vomiting, loss of appetite, diarrhoea and a metallic taste. Hypersensitivity reactions, which are occasionally severe, may occur in rare cases as skin rash, itching, urticaria and angioneurotic oedema. As with related compounds, T-zol may cause transient leukopenia. Other rarely reported side effects are headache, tiredness, furry tongue and dark urine.
Cautions & Contraindications
Warnings & Precautions
Compounds with a similar chemical structure have been linked to various neurological effects, including dizziness, vertigo, poor coordination, and ataxia. If any abnormal neurological signs appear during treatment with T-zol, the medicine should be stopped. Use in Pregnancy and Lactation: T-zol should not be used during the first trimester of pregnancy. Although there is no evidence that it causes harm later in pregnancy, using it during the second and third trimesters should only be considered if the expected benefit to the mother outweighs the possible risk to her and the foetus. T-zol passes into breast milk at levels similar to those found in the blood, and it can remain detectable in breast milk for up to 72 hours after a dose. Breast-feeding should be paused during treatment with T-zol and for 3 days after the final dose.
Contraindications
Tinidazole should not be used in patients who currently have, or have previously had, a blood dyscrasia, as is the case with other structurally similar compounds; that said, clinical and animal studies have not shown any lasting blood abnormalities linked to the drug. It should also be avoided in patients with organic neurological disorders, and it must not be given to anyone with a known hypersensitivity to tinidazole.