Pricing
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These brands contain the same active ingredient (Ropinirole). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Perkirol is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosing for Parkinson's disease: The recommended starting dose for Parkinson's disease is 0.25 mg three times daily. Based on individual patient therapeutic response and tolerability, the dosing should then be titrated with weekly increments as needed, as described below. Maximum recommended total daily dose is 24 mg (8 mg three times daily). Week 1: 0.25 mg three times daily. Total daily dose 0.75 mg. Week 2: 0.5 mg three times daily. Total daily dose 1.50 mg. Week 3: 0.75 mg three times daily. Total daily dose 2.25 mg. Week 4: 1 mg three times daily. Total daily dose 3 mg. Dosing for Restless Legs Syndrome: The recommended adult starting dose for RLS is 0.25 mg once daily, taken 1 to 3 hours before bedtime. After 2 days, if necessary, the dose can be increased to 0.5 mg once daily, and to 1 mg once daily at the end of the first week of dosing, then adjusted further as shown below as needed to achieve efficacy. Dosing titration should be based on individual patient therapeutic response and tolerability, up to a maximum recommended dose of 4 mg daily. Days 1 and 2: 0.25 mg once daily, 1 to 3 hours before bedtime. Days 3 to 7: 0.5 mg once daily, 1 to 3 hours before bedtime. Day 2 (of further titration): 1 mg once daily, 1 to 3 hours before bedtime. Day 3: 1.5 mg once daily, 1 to 3 hours before bedtime. Day 4: 2 mg once daily, 1 to 3 hours before bedtime. Day 5: 2.5 mg once daily, 1 to 3 hours before bedtime. Day 6: 3 mg once daily, 1 to 3 hours before bedtime. Day 7: 4 mg once daily, 1 to 3 hours before bedtime.
Side Effects
Perkirol commonly causes fainting, drowsiness, hallucinations, and dizziness, along with nausea or vomiting and uncontrolled, sudden movements. Some people also experience swelling in the legs, fatigue, confusion, headache, an upset stomach, abdominal pain or discomfort, and increased sweating, among other effects.
Cautions & Contraindications
Warnings & Precautions
Patients treated with Perkirol have reported falling asleep while engaged in daily activities. Dopamine agonists, based on clinical trials and clinical experience, appear to impair the body's normal regulation of blood pressure, which can result in orthostatic hypotension.
Contraindications
This medicine should not be used by anyone who is hypersensitive to Ropinirole.