Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Peranel is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Perampanel can be taken without regard to food. The dosage of Perampanel is as follows- Starting dose: 2 mg once daily at bedtime. May increase dose based on clinical response and tolerability by increments of 2 mg once daily no more frequently than at weekly intervals. Recommended maintenance dose in monotherapy or adjunctive therapy for partial-onset seizures: 8 mg to 12 mg once daily at bedtime. Recommended maintenance dose in adjunctive therapy for primary generalized tonic-clonic seizures: 8 mg once daily at bedtime. Mild and Moderate Hepatic Impairment: Maximum recommended daily dose is 6 mg (mild) and 4 mg (moderate) once daily at bedtime. Severe Hepatic Impairment: Not recommended. Severe Renal Impairment: Not recommended.Elderly: Increase dose no more frequently than every 2 weeks.
Side Effects
Peranel may cause Serious Psychiatric and Behavioral Reactions, Suicidal Behavior and Ideation, Dizziness, Somnolence, Fatigue, Irritability, Falls, Nausea, Ataxia, Balance Disorder etc.
Cautions & Contraindications
Warnings & Precautions
Suicidal Behavior and Ideation: Monitor for suicidal thoughts or Behaviour. Neurologic Effects: Monitor for dizziness, gait disturbance, somnolence and fatigue. Falls: Monitor for falls and injuries. Drug Reaction with Eosinophilia and Systemic Symptoms/Multi-organ Hypersensitivity: Discontinue if no alternate etiology. Withdrawal of Antiepileptic Drugs: In patients with epilepsy, there may be an increase in seizure frequency.
Contraindications
None.