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These brands contain the same active ingredient (Nortriptyline). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Nortin is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Depression: start with a low dose and increase gradually as needed, up to 75-100 mg daily (either divided through the day or as one single dose); do not exceed 150 mg daily. In adolescents and elderly patients, 30-50 mg daily in divided doses is usual. For nerve (neuropathic) pain: start at 10 mg daily at night, raising gradually if needed to 75 mg daily; doses above this should only be used under a specialist's supervision. Or take as directed by your physician.
Side Effects
Dry mouth, constipation, blurred vision, tremor, sedation, sweating, rashes, and behavioral disturbances may occur.
Cautions & Contraindications
Warnings & Precautions
Nortin should be used cautiously in patients with cardiovascular disease, including heart failure or arrhythmias, and such patients should have their heart function and ECG monitored during treatment. At high doses, it has been reported to cause QTc prolongation, arrhythmias, sinus tachycardia, and slowed conduction. Myocardial infarction and stroke have also been reported with drugs of this class.
Contraindications
Concurrent use with a monoamine oxidase (MAO) inhibitor is contraindicated, as hyperpyretic crises, severe convulsions, and fatalities have been reported when similar tricyclic antidepressants were combined with these drugs. The MAO inhibitor should be stopped at least two weeks before starting Nortriptyline. Nortriptyline must not be given to patients who are hypersensitive to it, and caution is warranted since cross-sensitivity with other dibenzazepine compounds is possible. Its use is also contraindicated during the acute recovery phase following a myocardial infarction.