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Other brands with the same active ingredient
These brands contain the same active ingredient (Cilnidipine). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Mydipine-10 is indicated for:
Pharmacology
Cilnidipine is a dihydropyridine calcium-channel blocker. Cilnidipine binds to the dihydropy-ridine binding sites of the L-type voltage dependent calcium channel and inhibits Ca2+ influx across the cell membranes of vascular smooth muscle cells via this channel, consequently vascular smooth muscle is relaxed, causing vasodilation. Cilnidipine inhibits Ca2+ influx via N-type voltage dependent calcium channels in the sympathetic nerve cell membrane. The inhibition of Ca2+ influx via N-type voltage dependent calcium channel was observed over a similar range of drug concentrations to those inhibiting L-type voltage dependent Ca2+ channels. Consequently, release of norepinephrine from sympathetic nerve terminals would be inhibited. Cilnidipine is considered to suppress the reflex increase in heart rate after blood pressure reduction.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults: 5-10 mg once daily after breakfast. Maximum dose: 20 mg once daily. Pediatric use: The safety of Cilnidipine in pediatric patients has not been established.Elderly use: Since the elderly may be more susceptible to hypotension, therapy should be initiated with the lowest possible dose (5 mg).
Side Effects
The most common side effects of Cilma are: Dizziness; flushing; headache; hypotension; peripheral oedema; palpitations; GI disturbances; increased micturition frequency; lethargy; eye pain; depression.
Cautions & Contraindications
Warnings & Precautions
Cilma should be administered with care in the following patients: patients with serious hepatic dysfunction, patients with a history of serious adverse reactions to calcium antagonists. During the discontinuation, the dosage should be gradually decreased under close observation.
Contraindications
Cilnidipine is contraindicated in patients with known sensitivity to Cilnidipine or any of the excipients or patients having cardiogenic shock, recent MI or acute unstable angina and severe aortic stenosis.
Pregnancy & Breastfeeding
Cilnidipine should not be administered in pregnant woman or woman having possibilities of being pregnant. It is also advisable to avoid the administration of Cilnidipine to nursing mothers. However, if the administration is indispensable, the patient should be instructed to discontinue lactation.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store below 30°C, protected from light and moisture. Keep away from reach out of the children.
Drug Interactions
Common questions about Mydipine-10 10 mg
What is Mydipine-10 10 mg Tablet?
Mydipine-10 10 mg Tablet is a medicine that contains Cilnidipine. It is made by Drug International Ltd., Gopalpur. It belongs to the Calcium-channel blockers group of medicines.
What is Mydipine-10 used for?
Mydipine-10 is used for: Hypertension, Diabetes Mellitus.
What are the side effects of Mydipine-10?
The most common side effects of Cilma are: Dizziness; flushing; headache; hypotension; peripheral oedema; palpitations; GI disturbances; increased micturition frequency; lethargy; eye pain; depression.
Can I take Mydipine-10 during pregnancy or while breastfeeding?
Cilnidipine should not be administered in pregnant woman or woman having possibilities of being pregnant. It is also advisable to avoid the administration of Cilnidipine to nursing mothers. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Mydipine-10?
Store below 30°C, protected from light and moisture. Keep away from reach out of the children.
Can I take other medicines with Mydipine-10?
Some medicines can interact with Cilnidipine, for example: Erythromycin, Carbamazepine, Rifampicin, Cimetidine, Phenytoin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Mydipine-10?
Mydipine-10 is a prescription (Rx) medicine. Take it as your doctor advises.