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Other brands with the same active ingredient
These brands contain the same active ingredient (Moxonidine). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Moxodin 0.4 is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Treatment should be started with 200 micrograms in the morning. The dose may be titrated after three weeks to 400 micrograms given as single dose or as divided daily doses (morning and evening) until a satisfactory response is achieved. If the response is still unsatisfactory after a further 3 weeks treatment, the dosage can be increased up to a maximum of 600 micrograms in divided doses (morning and evening). A single dose of 400 micrograms and a daily dose of 600 micrograms of Moxonidine should not be exceeded. Moxonidine may be taken with or without food.
Side Effects
Asthenia, Headache, Pain, Abdominal Pain Back Pain Dizziness, Dry mouth, Somnolence, Vertigo
Cautions & Contraindications
Warnings & Precautions
Cessation of combination therapy with beta-blockers: Stopping combination therapy with Sympres and a beta-blocker suddenly may cause rebound hypertension. If this combination therapy needs to be stopped, the beta-blocker should be withdrawn first, with Sympres discontinued a few days later. Blood pressure should be monitored regularly throughout the withdrawal period. Atrioventricular block: Cases of varying degrees of AV block have been reported after Sympres treatment in real-world use following marketing. Based on these reports, a role for Sympres in delaying atrioventricular conduction cannot be completely ruled out. Caution is therefore recommended when treating patients who may be predisposed to AV block. In patients with 1st degree AV block, special care should be taken to avoid bradycardia, and Sympres must not be used in higher degree AV blocks. Since Sympres is excreted mainly through the kidneys, it should be given with caution to patients with renal impairment, and the dose should be carefully titrated in these patients, particularly at the start of treatment. This product should not be taken by patients with rare hereditary conditions such as galactose intolerance, total lactose deficiency, or glucose-galactose malabsorption.
Contraindications
Hypersensitivity to any component Sick sinus syndrome Bradycardia (resting heart rate <50 beats/minute) AV-block 2nd and 3rd degree Cardiac insufficiency