Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Save on this medicine
Same active ingredient — pay up to 89% less
These brands contain the same active ingredient (Misoprostol). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Misotab is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Benign gastric and duodenal ulceration and NSAID associated ulceration: 800 mcg daily, given in 2 to 4 divided doses with breakfast or main meals and at bedtime. Treatment should be continued for at least 4 weeks and may be continued for up to 8 weeks if required. Prophylaxis of NSAID-induced gastric and duodenal ulcer: 200 mcg 2 to 4 times daily, taken with the NSAID. If this dose cannot be tolerated, a dose of 100 mcg can be used. Misoprostol should be taken for the duration of NSAID therapy as prescribed by the physician. Induction of labor: Place 25 mcg in the posterior fornix of the vagina. Repeat every 6 hours if necessary until the maximum total dose of 200 mcg of misoprostol is reached. Fetal heart rate and uterine contractions should be monitored. Alternatively, 100 mcg may be taken orally. If cervical ripening or active labor does not occur, a repeated dose of 100 to 200 mcg of oral misoprostol is given every 4 hours until labor is established, as shown by a Bishop score of 7 or more. The maximum number of doses is 6. Maternal vital signs, fetal heart rate and contractions should be monitored. Oxytocin can be started 4 hours after the last dose of misoprostol. The physician should be notified of any signs of fetal distress or tetanic uterine contractions. Oral misoprostol therapy should be monitored by a physician. Prevention of postpartum hemorrhage: 600 mcg orally immediately following delivery. Treatment of postpartum hemorrhage: 600 mcg orally or 1000 mcg rectally.
Side Effects
Cytomis is generally well tolerated. The side effects most often reported with Cytomis treatment involve the GI tract (gastrointestinal system) and include diarrhea, abdominal pain, dyspepsia (indigestion), flatulence, nausea, vomiting, rashes and dizziness. Diarrhea can be kept to a minimum by taking the medicine after meals and at bedtime, and by not taking it together with a magnesium-containing antacid or any other antacid that has a laxative effect.
Cautions & Contraindications
Warnings & Precautions
When used to prevent or treat stomach and duodenal ulcers caused by NSAIDs: Cytomis is contraindicated in pregnant women and should not be used in women who are able to become pregnant unless they need NSAID therapy. Women who are able to become pregnant should be told that they must not be pregnant when Cytomis treatment is started, and that they must use an effective method of contraception while taking Cytomis. When used to induce labour: The pregnancy should have completed 38 weeks of gestation by reliable dating, or lung maturity should be shown by an L/S ratio above 2.0 or a positive phosphatidyl glycerol test, or the pregnancy should have completed 36 weeks of gestation with a maternal or fetal medical reason for inducing labour. Inducing labour is contraindicated in acute fetal distress, abruptio placenta, placenta previa, or unexplained vaginal bleeding. The fetus should be in vertex presentation.
Contraindications
Misoprostol should not be used by anyone with a known allergy to prostaglandins. It is also contraindicated in pregnancy.