Indications & Uses
Mirtazapine Orally 45 is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual starting dose of mirtazapine tablets for adults is 15 mg a day, taken once, preferably in the evening or just before sleep. Most people are treated with a dose between 15 and 45 mg a day. If there is no response at 15 mg, the dose may be raised to 30 mg, and up to a maximum of 45 mg a day. Mirtazapine stays in the body for a long time, with an elimination half-life of about 20 to 40 hours. Because of this, the dose should not be changed more often than every 1 to 2 weeks. That gap gives the body enough time to show its response to a given dose. Mirtazapine is not recommended for use in children. If you miss a dose of mirtazapine, take it as soon as you remember, unless it is nearly time for the next dose. If it is close to the time of the next dose, skip the missed one and take the next dose at the usual time. Never take a double dose or more than the dose your doctor has prescribed.
Side Effects
The most common side effects of Mirez (mirtazapine) are dizziness, drowsiness, dry mouth, increased appetite and weight gain, among others.
Cautions & Contraindications
Warnings & Precautions
Patients, their families and their caregivers should be encouraged to watch for anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness), hypomania, mania, other unusual changes in behavior, worsening of depression, and suicidal ideation. This matters most early in antidepressant treatment and whenever the dose is adjusted up or down. Patients who are going to receive Mirez should be warned about the risk of developing agranulocytosis. Because of its prominent sedative effect, Mirez may impair judgment, thinking and, particularly, motor skills. Clinically significant ALT (SGPT) elevations (≥3 times the upper limit of the normal range) may occur.
Contraindications
Hypersensitivity: Mirtazapine should not be used by anyone with a known hypersensitivity to Mirtazapine or to any of its excipients. Monoamine Oxidase Inhibitors: Mirtazapine must not be taken together with a monoamine oxidase (MAO) inhibitor. It should also be avoided within 14 days of starting or stopping treatment with an MAOI.