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Same active ingredient — pay up to 8% less
These brands contain the same active ingredient (Imipenem + Cilastatin). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Maxipen is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The dosage in adult patients: This should be based on suspected or confirmed pathogen susceptibility.For adult patients with normal renal function (creatinine clearance of greater than or equal to 90 mL/min), the recommended dosage regimens are: 500 mg every 6 hours OR 1000 mg every 8 hours OR 1000 mg every 6 hours.A reduction in dose must be made for a patient with a creatinine clearance of less than 90 mL/min.Patients with creatinine clearances of less than 15 mL/min should not receive this combination unless hemodialysis is instituted within 48 hours.Reconstitute this vial with appropriate diluent and dilute the reconstituted suspension with an appropriate infusion solution before administering by intravenous infusion.Recommended Dosage in Pediatric Patients for Non-CNS Infections: Greater than or equal to 3 Months of Age: 15-25 mg/kg in every 6 hoursLess than or equal to 3 months of age (Greater than or equal to 1,500 g body weight): 4 weeks to 3 months of age: 25 mg/kg in every 6 hours 1 to 4 weeks of age: 25 mg/kg in every 8 hours Less than 1 week of age: 25 mg/kg in every 12 hours Doses less than or equal to 500 mg should be given by intravenous infusion over 20 to 30 minutes. Doses greater than 500 mg should be given by intravenous infusion over 40 to 60 minutes Recommend that the maximum total daily dosage not exceed 4g/day.
Side Effects
Phlebitis Nausea, diarrhea, vomiting Rash, pruritus, urticaria Pain injection site, erythema at injection site, vein induration Fever Hypotension Seizures, dizziness, somnolence
Cautions & Contraindications
Warnings & Precautions
Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. If an allergic reaction to Maxipen occurs, discontinue the drug immediately.Seizure Potential: Seizures and other CNS adverse reactions, such as confusional states and myoclonic activity, have been reported during treatment with Maxipen. If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of Maxipen re-examined to determine whether it should be decreased or the antibacterial drug discontinued.
Contraindications
Hypersensitivity to any component of this combination.