Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Other brands with the same active ingredient

These brands contain the same active ingredient (Amitriptyline Hydrochloride + Chlordiazepoxide). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.

Indications & Uses

Limitrol is indicated for:

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Optimum dosage varies with the severity of the symptoms and the response of the individual patient. When a satisfactory response is obtained, the dosage should be reduced to the smallest amount needed to maintain the remission. The larger portion of the total daily dose may be taken at bedtime. In some patients, a single dose at bedtime may be sufficient. An initial dosage of 3 or 4 tablets daily in divided doses is generally satisfactory, or as directed by the physician.

Side Effects

Side effects: Treatment with Limitrol has been linked to several symptoms that also occur commonly in depression itself, including loss of appetite, tiredness, weakness, restlessness and sluggishness. Adverse reactions: The most frequently reported reactions are drowsiness, dry mouth, constipation, blurred vision, dizziness and bloating. Less commonly, patients have experienced vivid dreams, impotence, tremor, confusion and a stuffy nose.

Cautions & Contraindications

Warnings & Precautions

Use with caution in patients who have had seizures in the past. If Limitrol is prescribed for someone with an overactive thyroid, or who is already on thyroid medication, they should be monitored closely. The usual care should be taken when treating patients whose kidney or liver function is impaired. Children and adolescents being treated with antidepressants, for any reason, should be watched carefully for signs of worsening symptoms, suicidal thoughts, or unusual changes in behavior.

Contraindications

This medicine is not suitable for anyone who is hypersensitive to benzodiazepines or tricyclic antidepressants. It should also not be taken together with a monoamine oxidase inhibitor.

Last updated: 15 Aug 2026