Indications & Uses
Lerof is indicated for:
Pharmacology
Levofloxacin eye drops is a sterile solution applied to the eye. It is a synthetic, broad spectrum, third generation fluoroquinolone bactericidal antibiotic, active against many Gram-positive and Gram-negative ocular pathogens. It works by inhibiting the bacterial enzymes topoisomerase IV and DNA gyrase, which are needed for DNA replication, transcription, repair and recombination.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
0.5% eye drop: Adults and children 1 year of age and older: Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 2 hours while awake, up to 8 times per day. Days 3 through 7: Instill 1 to 2 drops in the affected eye(s) every 4 hours while awake, up to 4 times per day. 1.5% eye drop: Adults and children 6 years of age and older: Days 1 through 3: Instill one to two drops in the affected eye(s) every 30 minutes to 2 hours while awake, and again approximately 4 and 6 hours after retiring. Day 4 through treatment completion: Instill one to two drops in the affected eye(s) every 1 to 4 hours while awake. 1.5% ear drop: The usual dosage is 6 to 10 drops in the ear twice a day. After applying the ear drops, perform an ear bath for about 10 minutes. The number of doses may be increased or decreased as appropriate depending on the symptoms. Children under 1 year: Safety and effectiveness of Levofloxacin below 1 year of age have not been established.
Side Effects
Side effects are generally uncommon. Around 1-3% of patients may notice temporary blurred vision, fever, a sensation of something in the eye, headache, transient burning or discomfort in the eyes, sore throat, or sensitivity to light. Less than 1% of patients experience allergic reactions, eyelid swelling, dryness of the eyes, or itching in the eyes.
Cautions & Contraindications
Warnings & Precautions
Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi. If a superinfection develops, treatment should be stopped and an appropriate alternative therapy started.
Contraindications
Levofloxacin should not be used in patients known to be hypersensitive to levofloxacin, to other quinolone antibiotics, or to any other ingredient in this medication.
Pregnancy & Breastfeeding
Pregnancy Category C. Levofloxacin should only be used in pregnancy if the expected benefit to the mother outweighs any possible risk to the unborn baby. It is not known whether Levofloxacin passes into human breast milk, so nursing mothers should use Levofloxacin eye drops with caution.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep the levofloxacin eye drops away from light and store them in a cool, dry place, at 15°-25° C. Keep them out of reach of children.
Drug Interactions
Common questions about Lerof 500 mg
What is Lerof 500 mg Tablet?
Lerof 500 mg Tablet is a medicine that contains Levofloxacin. It is made by United Chemicals & Pharmaceuticals Ltd. It belongs to the 4-Quinolone preparations group of medicines.
What is Lerof used for?
Lerof is used for: Otitis Media, Conjunctivitis.
What are the side effects of Lerof?
Side effects are generally uncommon. Around 1-3% of patients may notice temporary blurred vision, fever, a sensation of something in the eye, headache, transient burning or discomfort in the eyes, sore throat, or sensitivity to light.
Can I take Lerof during pregnancy or while breastfeeding?
Pregnancy Category C. Levofloxacin should only be used in pregnancy if the expected benefit to the mother outweighs any possible risk to the unborn baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Lerof?
Keep the levofloxacin eye drops away from light and store them in a cool, dry place, at 15°-25° C. Keep them out of reach of children.
Can I take other medicines with Lerof?
Some medicines can interact with Levofloxacin, for example: Theophylline, Caffeine, Calcium Orotate, Magnesium Hydroxide, Ibandronic Acid & Calcium Orotate, Dexamethasone + Levofloxacin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Lerof?
Lerof is a prescription (Rx) medicine. Take it as your doctor advises.