Indications & Uses
LEQVIO is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The recommended dosage of Inclisiran for adults and pediatric patients aged 12 years and older is 284 mg administered as a single subcutaneous injection initially, again at 3 months, and then every 6 months.If a planned dose is missed by less than 3 months, administer Inclisiran and maintain dosing according to the patient’s original schedule.If a planned dose is missed by more than 3 months, restart with a new dosing schedule - administer Inclisiran initially, again at 3 months, and then every 6 months.Assess LDL-C when clinically indicated. The LDL-lowering effect of Inclisiran may be measured as early as 30 days after initiation and anytime thereafter without regard to timing of the dose.
Side Effects
Common adverse reactions in clinical trials (≥ 3%): injection site reaction, arthralgia, and bronchitis.
Cautions & Contraindications
Warnings & Precautions
Hypersensitivity Reactions: Have been reported in patients treated with LEQVIO. Advise patients on the signs and symptoms of hypersensitivity reactions and instruct patients to seek medical attention promptly.
Contraindications
Prior serious hypersensitivity to inclisiran or any of the excipients in Inclisiran.