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These brands contain the same active ingredient (Levamlodipine Maleate). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Esodip is calcium channel blocker and may be used alone or in combination with other antihypertensive agents for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Route of administration: Should be taken orally.Dosage: The usual initial antihypertensive oral dose of Levamlodipine is 2.5 mg once daily, and the maximum dose is 5 mg once daily.Adult and elderly patients: Elderly patients, or patients with hepatic insufficiency may be started on 1.25 mg once daily and this dose may be used when adding Levamlodipine to other antihypertensive therapy. Dosage needs to be adjusted according to blood pressure goals. 7 to 14 days waiting period between titration steps is needed. Titration needs to be done more rapidly, however, if clinically warranted, provided the patient is assessed frequently. Use in children and adolescents: The effective antihypertensive oral dose in pediatric patients ages 6-17 years is 1.25 mg to 2.5 mg once daily. Doses in excess of 2.5 mg daily have not been studied in pediatric patients.
Side Effects
Common: Difficulty in breathing, Dizziness, Reflex Tachycardia, Hypotension, Abdominal Pain & Edema.Rare: Diarrhea, Back pain, Headache, Fatigue & Nausea.
Cautions & Contraindications
Warnings & Precautions
Hypotension: Symptomatic hypotension is possible, particularly in patients with severe aortic stenosis. Because of the gradual onset of action, acute hypotension is unlikely.Increased Angina or Myocardial Infarction: Worsening angina and acute myocardial infarction can develop after starting or increasing the dose of amlodipine, particularly in patients with severe obstructive coronary artery disease.Patients with Hepatic Failure: Because amlodipine is extensively metabolized by the liver and the plasma elimination half-life (t½) is 56 hours in patients with impaired hepatic function, titrate slowly when administering amlodipine to patients with severe hepatic impairment.
Contraindications
S-Amlodipine is contraindicated in patients with known sensitivity to amlodipine.