Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
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Icosa is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The daily dose of Vescap is 4 grams per day taken as Two 1 gm capsules twice daily with food. Advise patients to swallow capsules whole. Do not break open, crush, dissolve, or chew Vescap.Renal Impairment: Icosapent ethyl has not been studied in patients with renal impairment.Hepatic Impairment: In patients with hepatic impairment, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels should be monitored periodically during therapy with Icosapent ethyl.Pediatric use: Safety and effectiveness in pediatric patients have not been established.Geriatric use: Icosapent ethyl is safe and effective in geriatric patients.
Side Effects
Common adverse reactions in the cardiovascular outcomes trial: Musculoskeletal pain, peripheral edema, constipation, gout, and atrial fibrillation. Common adverse reactions in the hypertriglyceridemia trials: arthralgia and oropharyngeal pain.
Cautions & Contraindications
Warnings & Precautions
Atrial fibrillation/flutter: Vescap was associated with an increased risk of atrial fibrillation or atrial flutter requiring hospitalization in a double-blind, placebo-controlled trial. The incidence of atrial fibrillation was greater in patients with a previous history of atrial fibrillation or atrial flutter.Potential for allergic reactions in patients with fish allergy: Vescap contains ethyl esters of the omega-3 fatty acid, eicosapentaenoic acid (EPA), obtained from the oil of fish. It is not known whether patients with allergies to fish and/or shellfish are at increased risk of an allergic reaction to Vescap. If patients have known hypersensitivity to fish and/or shellfish about the potential for allergic reactions then they should discontinue Vescap and seek medical attention.Bleeding: Vescap was associated with an increased risk of bleeding in a double-blind, placebo-controlled trial. The incidence of bleeding was greater in patients receiving concomitant antithrombotic medications, such as aspirin, clopidogrel, or warfarin.
Contraindications
This is contraindicated in patients with known hypersensitivity (e.g., anaphylactic reaction) to Icosapent Ethyl or any of its components.