Indications & Uses
Hepavax-B is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage Neonates, infants and children upto 19 years of age: The recommended dose of Hepatitis B vaccine (rDNA) is >10 mcg of antigen protein in 0.5 ml.Adults 19 years of age and older: The recommended dose of Hepatitis B vaccine (rDNA) is >20 mcg of antigen in 1 ml.Primary immunization schedule for all ages:The usual immunization schedule consists of 3 doses of vaccine- First dose: at elected date Second dose: 1 month after first dose Third dose: 6 months after first dose or accelerated schedule consists of 4 doses of vaccine- First dose: at elected date Second dose: 1 month after first dose Third dose: 2 months after first dose Fourth dose: 12 months after first dose Accelerated schedule confer protection more quickly and is expected to provide better patient compliance.Neonate born to hepatitis B surface antigen-positive mother, 4 doses of 10 micrograms: First dose: at birth with Hepatitis B immunoglobulin injection (separate site) Second dose: 1 month after first dose Third dose: 2 months after first dose Fourth dose: 12 months after first dose For travellers departing within 1 month, adult over 18 years, First dose: at elected date Second dose: 7 days after first dose Third dose: 21 days after first dose Fourth dose: 12 months after first dose Renal insufficiency (including haemodialysis patients), adult and child over 16 years 4 doses of 40 micrograms- First dose: at the appropriate date Second dose: 1 month after first dose Third dose: 2 months after first dose Fourth dose: 6 months after first dose Immunization schedule and booster doses may need to be adjusted in those with low antibody concentration.Booster vaccinations: For persons with normal immune status who have been vaccinated, booster doses ofHepatitis B vaccine has not been established. However, booster doses are recommended for hemodialysis patients or other immunocompromised persons.
Side Effects
HB-fix is generally well tolerated. Most recipients of HB-fix experience some reactions upon vaccination. These are generally moderate and short. They mainly consist of local reactions at the injection site (erythema, induration and tenderness). Systemic reactions (malaise, headache, diarrhea, vomiting, myalgia and elevated temperature) are reported less commonly. In very rare cases allergic type reactions (pruritus, rash, urticaria) may be observed.
Cautions & Contraindications
Contraindications
Hypersensitivity to any component of the vaccine, including yeast, is a contraindication. This vaccine is contraindicated in patients with previous hypersensitivity to any Hepatitis B virus containing vaccine.