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Other brands with the same active ingredient
These brands contain the same active ingredient (Clotrimazole). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Gyno-Clozox
Other strengths and forms by Unimed Unihealth Pharmaceuticals Ltd.
Indications & Uses
Gyno-Clozox is indicated for:
Pharmacology
Clotrimazole works mainly by damaging the permeability barrier in the fungal cell membrane. It inhibits the biosynthesis of ergosterol, a substance essential to fungal cell membranes. When ergosterol synthesis is blocked, whether completely or partially, the cell can no longer build an intact, functional membrane. Since ergosterol directly promotes fungal cell growth in a hormone-like way, this rapid disruption leads to a dose-dependent inhibition of fungal growth.
Though the resulting drop in ergosterol, caused by inhibition of the enzyme lanosterol 14-demethylase (also known as CYP51), is considered the main reason for clotrimazole's antifungal action, the drug also produces other pharmacological effects. These include inhibiting sarcoplasmic reticulum Ca2+ ATPase, depleting intracellular calcium, and blocking calcium-dependent potassium channels and voltage-dependent calcium channels. Clotrimazole's action on these targets explains additional effects of the drug that are separate from its antifungal activity.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Apply a thin layer to the infected areas two to three times daily and rub it in gently. Because it works so well, only a small amount of cream is usually needed to cover an area about the size of the palm. Using Clotrimazole Cream reliably and for a long enough period is important for the treatment to succeed fully. How long treatment is needed varies, depending among other things on how widespread the infection is and where it is located. Recommended treatment duration is about 3 to 4 weeks for dermatomycoses, 1 to 2 weeks for candida vulvitis and candida balanitis, and about 3 weeks for erythrasma and pityriasis versicolor. For fungal infections of the feet, treatment should be continued for about 2 weeks after all signs of the disease have disappeared, to prevent it from returning. After washing, the feet should be dried thoroughly, especially between the toes. Clotrimazole Cream is odorless, washes off easily and does not stain clothing.
Apply this sparingly to the affected areas and rub it in gently, two or three times daily.
Side Effects
Well tolerated when used on the skin, Clotzol does not produce systemic effects with topical use. A small number of patients notice mild local irritation or a burning sensation, but this is minor and not considered harmful.
Cautions & Contraindications
Warnings & Precautions
Fungizol ointment should be stopped if the skin becomes irritated or shows signs of sensitivity.
Contraindications
Hypersensitivity to clotrimazole.
Pregnancy & Breastfeeding
Clotrimazole should only be used during pregnancy if a physician judges it necessary.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Clotrimazole has been shown to be safe and effective in children when it is used for its indicated purpose and at the recommended dose.
Overdose
If Clotrimazole is swallowed by accident, supportive measures should be taken.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep below 25°C temperature, away from light & moisture. Keep out of the reach of children.
Drug Interactions
Common questions about Gyno-Clozox 200 mg
What is Gyno-Clozox 200 mg Vaginal Tablet?
Gyno-Clozox 200 mg Vaginal Tablet is a medicine that contains Clotrimazole. It is made by Unimed Unihealth Pharmaceuticals Ltd. It belongs to the Drugs for subcutaneous and mycoses group of medicines.
What is Gyno-Clozox used for?
Gyno-Clozox is used for: Skin and Soft Tissue Infection.
What are the side effects of Gyno-Clozox?
Well tolerated when used on the skin, Clotzol does not produce systemic effects with topical use. A small number of patients notice mild local irritation or a burning sensation, but this is minor and not considered harmful.
Can I take Gyno-Clozox during pregnancy or while breastfeeding?
Clotrimazole should only be used during pregnancy if a physician judges it necessary. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Gyno-Clozox?
If Clotrimazole is swallowed by accident, supportive measures should be taken. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Gyno-Clozox?
Keep below 25°C temperature, away from light & moisture. Keep out of the reach of children.
Can I take other medicines with Gyno-Clozox?
Some medicines can interact with Clotrimazole, for example: Brinzolamide + Timolol, Methylergonovine Maleate. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Gyno-Clozox?
Gyno-Clozox is a prescription (Rx) medicine. Take it as your doctor advises.