Pricing
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All price changes →Indications & Uses
Active management of the third stage of labour; treatment and prevention of postpartum haemorrhage; control of excessive uterine bleeding; and bleeding following childbirth or abortion.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Intramuscular use in adults: For active management of the third stage of labour, give 0.5 mg together with 5 units of oxytocin after delivery of the infant's anterior shoulder, or immediately after delivery. For treatment and prevention of postpartum haemorrhage, give 0.2 mg, which may be repeated every 2 to 4 hours as needed in severe bleeding. Intravenous use in adults: For excessive uterine bleeding, give 0.2 mg by IV injection over at least 1 minute. This may be followed by oral doses of 0.2 to 0.4 mg 2 to 4 times daily until the risk of uterine atony or haemorrhage has passed (usually 48 hours). Oral use in adults: For postpartum and post-abortion bleeding, give 0.2 to 0.4 mg 2 to 4 times daily until the risk of uterine atony and haemorrhage has passed (usually 48 hours), for a maximum duration of 1 week postpartum.
Side Effects
Nausea, vomiting, stomach pain, and diarrhoea may occur, along with headache, dizziness, and ringing in the ears. It can also cause chest pain, palpitations, a slowed heartbeat, temporary rise in blood pressure, and other irregular heart rhythms. Breathlessness, occasional skin rashes, and shock have also been reported.
Cautions & Contraindications
Warnings & Precautions
Breech and abnormal foetal presentation; hypertension; chronic anaemia; hepatic, renal, respiratory or cardiac impairment; toxemia; lactation; hypocalcaemia. Monitor BP, pulse and uterine response.
Contraindications
Contraindicated in pregnancy, during the 1st and 2nd stages of labour, and in patients with pre-eclampsia, eclampsia, threatened spontaneous abortion, or porphyria.