Indications & Uses
G-Adrenaline is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Cardiac arrest: Given by intravenous injection, 1 mg repeated every 2 to 3 minutes as needed. Endotracheal route: 2 to 3 mg given via an endotracheal tube, repeated as needed. Intracardiac route: 0.1 to 1 mg injected directly into the atrium of the heart. Intraspinal route: the usual dose is 0.2 to 0.4 mg added to the anesthetic spinal fluid mixture, to prolong the anesthetic action by limiting absorption. Anaphylaxis, asthma or severe bronchospasm: the adult dose is 0.25 to 0.5 mg. It may be repeated at 5 minute intervals until perfusion and respiratory status normalize. When diluting the dose, 1 mg of Adrenaline should be diluted in 9 ml of Normal Saline. Children: initially 10 mcg per kg body weight, not to exceed 250 mcg. This may be repeated every 3 to 5 minutes if needed, with subsequent doses of 100 mcg per kg.
Side Effects
Common side effects are anxiety, restlessness, dizziness, headache, palpitations, rapid pulse, tremors, weakness and coldness of the extremities may be reported even with small doses and especially when given in conjunction with local anaesthetics.
Cautions & Contraindications
Warnings & Precautions
The solution should not be used if it is pinkish or darker than slightly yellow, or if it contains a precipitate. Adrinor is readily destroyed by alkalies and oxidizing agents, including oxygen, chlorine, iodine, permanganates, chromates, nitrites and salts of easily reducible metals, especially iron. Adrinor should not be mixed with sodium bicarbonate, as the solution is then oxidised to adrenochrome and forms polymers. It should be administered slowly and with caution to elderly patients and to those with ischemic heart disease, hypertension, diabetes mellitus, hyperthyroidism or psychoneurosis. Extreme caution is required in patients with long-standing bronchial asthma and emphysema who have developed degenerative heart disease, as anginal pain may be induced when coronary insufficiency is present.
Contraindications
Contraindicated in hypertension, arteriosclerosis, coronary disease, and hyperthyroidism, and in patients taking monoamine oxidase inhibitors.