Indications & Uses
Fructose is used intravenously as a carbohydrate nutrient. It is converted to liver glycogen and metabolized more rapidly than dextrose without requiring insulin, so it may be used in diabetic patients. Fructose is indicated in patients requiring fluid replacement and caloric feeding. It is a better "nitrogen sparer" than glucose.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage: The volume and rate of infusion of fructose IV solution depend on the patient's requirements and the judgement of the attending physician, but the infusion rate should not exceed 0.5 to 1 gm per kg body weight per hour. The usual recommended flow rate for adults is 30 to 75 drops per minute, given intravenously.
Side Effects
Intravenous Fructose can lead to lactic acidosis and hyperuricemia. Giving it too quickly may also cause facial flushing, abdominal pain, and sweating.
Cautions & Contraindications
Warnings & Precautions
Fructose must not be given to patients with hereditary fructose intolerance, and should be used cautiously in those with impaired kidney function or severe liver damage. If rigors occur at any point during the infusion, stop it immediately. The solution should not be used if it is cloudy, contains particles, or has passed its expiry date.
Contraindications
Fructose shouldn't be used by people with certain inherited disorders of fructose metabolism, methanol poisoning, high uric acid levels, liver failure, or lactic acidosis.