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Other brands with the same active ingredient
These brands contain the same active ingredient (Trifluoperazine). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Flurazine 5 is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Schizophrenia and other psychoses: Adults and children over 12 years: the recommended starting dose is 2 to 5 mg twice daily, increased by 5 mg daily after 1 week, then at intervals of 3 days according to response. Children (6 to 12 years): dosage should be adjusted to the weight of the child and the severity of the symptoms. The starting dosage is 1 mg twice daily. Dosage may be increased gradually until symptoms are controlled or until side effects become troublesome, though it is usually not necessary to exceed 15 mg daily. Elderly: reduce the initial dose by at least half. Short term management of severe anxiety: Adults and children over 12 years: 1 to 2 mg twice daily, increased if necessary to 6 mg daily. Children (3 to 5 years): 1 mg daily. Children (6 to 12 years): up to 4 mg daily in divided doses. Elderly: reduce the initial dose by at least half. Antiemetic: Adults: 2 to 4 mg daily in divided doses, maximum 6 mg daily. Children 3 to 5 years: up to 1 mg daily; 6 to 12 years: up to 4 mg daily.
Side Effects
Common side effects include transient restlessness, dystonias, or symptoms resembling parkinsonism. Other CNS reactions include drowsiness, dizziness, fatigue, blurred vision, and seizures. Apart from these CNS effects, peripheral oedema, blood dyscrasias, and jaundice may occasionally occur. Tachycardia, constipation, urinary hesitancy and retention, and hyperpyrexia have been reported very rarely.
Cautions & Contraindications
Warnings & Precautions
Care should be taken when treating older patients, starting with a reduced initial dose. This group can be especially sensitive to the drug's effects, particularly extrapyramidal symptoms and drops in blood pressure. Similarly, caution is advised in patients with cardiovascular disease, including arrhythmias, and those with angina pectoris should also be treated carefully.
Contraindications
Trifluoperazine should not be given to patients who are comatose, who have a known blood disorder or liver damage, or who are hypersensitive to trifluoperazine or other phenothiazine drugs.