Pricing
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All price changes →Indications & Uses
Epleron is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Congestive heart failure following a recent heart attack: The usual dose of Eplerenone for this condition is 50 mg once daily. Treatment is generally started at 25 mg once daily, with the dose increased to the 50 mg once-daily target within about 4 weeks, as the patient is able to tolerate it. Eplerenone can be taken with or without food. Hypertension: Eplerenone may be used on its own or together with other blood pressure lowering medicines. The usual starting dose for hypertension is 50 mg once daily. If blood pressure is not adequately controlled on 50 mg once daily, the dose may be increased to 50 mg twice daily. Doses higher than this are not advised, since they do not lower blood pressure any further than 100 mg a day and carry a greater risk of high potassium levels in the blood. Use in children: The safety and effectiveness of Eplerenone in pediatric patients have not been established. Use in the elderly: No differences in overall effectiveness or safety were seen in geriatric patients compared with younger adults.
Side Effects
Headache, dizziness, diarrhoea, stomach pain, nausea, and cough or flu-like symptoms can occur while taking this medicine. Seek immediate medical attention if signs of a serious allergic reaction appear, such as rash, itching, swelling, severe dizziness, or trouble breathing.
Cautions & Contraindications
Warnings & Precautions
Aldonist should be used with caution in patients who have hyperkalemia, severe kidney disease, or diabetes with congestive heart failure after a recent heart attack, including those who also have proteinuria.
Contraindications
Eplerenone is contraindicated in hyperkalemia, severe renal impairment (creatinine clearance less than 30 ml/min), severe hepatic impairment. Concomitant use with potent CYPBA4 inhibitors like Ketoconazole, Itraconazole, Nefazodone, Troleandomycin, Clarithromycin, Ritonavir, and Nelfinavir or other potassium-sparing diuretics are also contraindicated.