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Other brands with the same active ingredient
These brands contain the same active ingredient (Allopurinol). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Alurol is indicated for reducing urate/uric acid formation in conditions where urate/uric acid deposition has already occurred (e.g. gouty arthritis, skin tophi, nephrolithiasis). Alurol is indicated for management of 2,8-dihydroxyadenine (2,8-DHA) renal stones related to deficient activity ... Read moreAlurol is indicated for reducing urate/uric acid formation in conditions where urate/uric acid deposition has already occurred (e.g. gouty arthritis, skin tophi, nephrolithiasis). Alurol is indicated for management of 2,8-dihydroxyadenine (2,8-DHA) renal stones related to deficient activity of adenine phospho ribosyltransferase. Alurol is indicated for the management of recurrent mixed calcium oxalate renal stones in the presence of hyperuricosuria, when fluid, dietary and similar measures have failed.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults: Doctors usually start allopurinol at a low dose, such as 100 mg per day, to limit the chance of side effects, and increase it only if the response in serum urate levels is not satisfactory. Extra care is needed when kidney function is poor. Suggested dosage schedules are 100 to 200 mg daily for mild conditions, 300 to 600 mg daily for moderately severe conditions, and 700 to 900 mg daily for severe conditions. Children: In children under 15 years, the dose is 10 to 20 mg per kg of body weight per day, up to a maximum of 400 mg daily. Use in children is rarely needed, except in malignant conditions (especially leukaemia) and certain enzyme disorders such as Lesch-Nyhan syndrome. Elderly: Without specific data to guide dosing, the lowest dose that gives a satisfactory reduction in urate should be used. Dosage in renal impairment: In severe renal insufficiency, it may be best to use less than 100 mg per day, or to give single doses of 100 mg at intervals longer than one day.
Side Effects
Rashes, gastrointestinal upset, and occasionally malaise, headache, dizziness, drowsiness, and disturbances of vision and taste may occur. Other reported effects include high blood pressure, hair loss, liver toxicity, nerve damage, breast enlargement in men, and blood disorders.
Cautions & Contraindications
Warnings & Precautions
Alurol should be stopped right away if a skin rash or any other sign of sensitivity develops. In patients with liver or kidney impairment, a reduced dose should be used. People being treated for high blood pressure or heart failure may also have some degree of reduced kidney function, so Alurol should be used cautiously in this group.
Contraindications
Allopurinol tablets should not be used by anyone who is known to be hypersensitive (allergic) to allopurinol.