Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Daconib is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The recommended dosage of Dacomitinib is 45 mg taken orally once daily, until disease progression or unacceptable toxicity occurs. Dacomitinib can be taken with or without food. Take Dacomitinib the same time each day. If the patient vomits or misses a dose, do not take an additional dose or make up a missed dose but continue with the next scheduled dose. First dose reduction Dose Level-30 mg Dose (Once Daily) Second dose reduction Dose Level-15 mg Dose.
Side Effects
Most common adverse reactions (incidence >20%) are diarrhea, rash, paronychia, stomatitis, decreased appetite, dry skin, decreased weight, alopecia, cough, and pruritus.
Cautions & Contraindications
Warnings & Precautions
Interstitial Lung Disease (ILD): Permanently discontinue Dacocent if ILD is confirmedDiarrhea: Withhold and reduce the dose of Dacocent based on the severityDermatologic Adverse Reactions: Withhold and reduce the dose of Dacocent based on the severityEmbryo-Fetal Toxicity: Dacocent can cause fetal harm. Advise females of reproductive potential to use effective contraception.