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Other brands with the same active ingredient
These brands contain the same active ingredient (Ezetimibe). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Cholinor is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The patient should follow a suitable lipid lowering diet and continue this diet throughout treatment with Ezetimibe. Adult Dose: The recommended dose is one Ezetimibe 10 mg tablet once daily. Ezetimibe can be taken at any time of day, with or without food. Use in the elderly: No dosage adjustment is required for elderly patients. Pediatric Use: For pediatric patients aged 10 to 17 years, no dosage adjustment is required, though clinical experience in pediatric and adolescent patients remains limited. When Ezetimibe is given together with a statin, the dosing instructions for that statin in adolescents should be consulted. For pediatric patients below age 10, Ezetimibe is not recommended, since safety and efficacy data in this age group are insufficient. Use in hepatic impairment: No dosage adjustment is required for patients with mild hepatic insufficiency (Child Pugh score 5 to 6). Treatment with Ezetimibe is not recommended for patients with moderate (Child Pugh score 7 to 9) or severe (Child Pugh score above 9) liver dysfunction. Use in renal impairment: No dosage adjustment is required for patients with renal impairment.
Side Effects
Ezetrol (used alone or together with an HMG-CoA reductase inhibitor) was generally well tolerated in clinical studies. The overall rate of adverse events reported with Ezetrol was similar to that seen with placebo, and a similar proportion of patients on Ezetrol and on placebo stopped treatment because of adverse events. Adverse reactions seen in patients treated with Ezetrol included the following. Common or very common: fatigue, gastro-intestinal disturbances, headache, muscle pain. Rare: anaphylaxis, angioedema, joint pain, hepatitis, hypersensitivity reactions, rash. Very rare: cholecystitis, gallstones, myopathy, pancreatitis, raised creatine kinase, rhabdomyolysis, and a drop in platelet count (thrombocytopenia).
Cautions & Contraindications
Warnings & Precautions
Concurrent use of Ezetrol with a specific HMG-CoA reductase inhibitor (statin) should follow the prescribing information provided for that particular statin.
Contraindications
Hypersensitivity to any component of this medication. The combination of Ezetimibe with an HMG-CoA reductase inhibitor is contraindicated in patients with active liver disease or unexplained persistent elevations in serum transaminases.