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These brands contain the same active ingredient (Cefpodoxime Proxetil). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and Adolescents (13 years and older)- Pharyngitis/tonsillitis: 100 mg 12 hourly, 5 to 10 days Acute maxillary sinusitis: 200 mg 12 hourly, 10 day Community-acquired pneumonia: 200 mg 12 hourly, 14 days Acute bacterial exacerbations of chronic bronchitis: 200 mg 12 hourly, 10 days Skin and skin structure: 400 mg 12 hourly, 7 to 14 days Uncomplicated urinary tract infection: 100 mg 12 hourly, 7 days Uncomplicated gonorrhea: single dose of 200 mg Rectal gonococcal infections in women: single dose of 200 mg Infants and Pediatric Patients (2 months to 12 years)- Acute otitis media: 5 mg/kg body weight 12 hourly, 5 days Pharyngitis /tonsillitis: 5 mg/kg body weight 12 hourly, 5 to 10 days Acute maxillary sinusitis: 5 mg/kg body weight 12 hourly, 10 days Patients with renal dysfunction: For patients with severe renal impairment (creatinine clearance <30ml/min) the dosing intervals should be increased to 24 hourly.Patients with liver cirrhosis: Cefpodoxime Proxetil pharmacokinetics in cirrhotic patients are similar to those in healthy subjects. Dose adjustment is not necessary in this population.
Side Effects
Xepodox has very few side effects. The side effects include diarrhea, nausea, skin & vaginal fungal infection, abdominal pain, headache, chest pain, myalgia, dyspepsia, dizziness, vertigo, cough etc. In children incidence of fungal skin rash is more than adults.
Cautions & Contraindications
Warnings & Precautions
In patients with transient or persistent reduction in urinary output due to renal insufficiency, the total daily dose of Xepodox should be reduced. Xepodox, like other cephalosporins, should be administered with caution to patients receiving concurrent treatment with potent diuretics. As with other broad spectrum antibiotics, prolonged use of Xepodox may result in overgrowth of non-susceptible organisms. Repeated evaluation of the patient’s condition is essential.
Contraindications
Cefpodoxime Proxetil is contraindicated in patients with a known allergy to Cefpodoxime or to the cephalosporin group of antibiotics.