Indications & Uses
Carmustine is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Recommended Dosage: As a single agent, 150 to 200 mg/m2 carmustine intravenously every 6 weeks as a single dose or divided into daily injections such as 75 to 100 mg/m2 on 2 successive days. Adjust dose for combination therapy or in patients with reduced bone marrow reserveAdminister reconstituted solution only as a slow intravenous infusion over at least 2 hours.
Side Effects
Most common adverse reactions (>1%) are nausea, vomiting, renal toxicity, pneumonitis, pulmonary toxicity, myelosuppression
Cautions & Contraindications
Warnings & Precautions
Administration Reactions: Extravasation may occur; monitor infusion site closely during administration.Carcinogenicity: Potentially carcinogenic to humans. Monitor patient periodically for such signs and apprise the patient of the symptoms for which they need to seek medical help.Ocular Toxicity: Has occurred when administered via unapproved intraarterial intracarotid route.Embryo-Fetal toxicity: Can cause fetal harm. Advise females of reproductive potential of the potential risk to a fetus and to avoid pregnancy.
Contraindications
Carmustine is contraindicated in patients with previous hypersensitivity to Carmustine or its components.