Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Capmaxen is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Patient Selection: Select patients for treatment with Capmatinib based on the presence of a mutation that leads to MET exon 14 skipping in tumor or plasma specimens. If a mutation that leads to MET exon 14 skipping is not detected in a plasma specimen, test tumor tissue if feasible.Recommended Dose: The recommended dosage of Capmatinib is 400 mg orally twice daily with or without food. Swallow Capmatinib tablets whole. Do not break, crush or chew the tablets. If a patient misses or vomits a dose, instruct the patient not to make up the dose, but to take the next dose at its scheduled time.
Side Effects
Lung or breathing problems Liver problems. Pancreas problems. Swelling of your hands or feet Nausea Muscle or bone pain Tiredness and weakness Vomiting Trouble breathing Cough Loss of appetite Changes in certain blood tests
Cautions & Contraindications
Warnings & Precautions
Interstitial Lung Disease (ILD): Immediately withhold Capmaxen in patients with suspected ILD/pneumonitis and permanently discontinue if no other potential causes of ILD/pneumonitis are identified.Hepatotoxicity: Monitor liver function tests (including ALT, AST, and total bilirubin) prior to the start of Capmaxen, every 2 weeks during the first 3 months of treatment, then once a month or as clinically indicated, with more frequent testing in patients who develop increased transaminases or bilirubin. Based on the severity of the adverse reaction, withhold, dose reduce, or permanently discontinue Capmaxen.Pancreatic Toxicity: Monitor amylase and lipase at baseline and regularly during treatment with Capmaxen. Based on the severity of the adverse drug reaction, temporarily withhold, dose reduce, or permanently discontinue Capmaxen.Risk of Photosensitivity: Advise patients to limit direct ultraviolet exposure during treatment with Capmaxen.Embryo-Fetal Toxicity: Based on findings from animal studies and its mechanism of action, Capmaxen can cause fetal harm when administered to a pregnant woman.