Save on this medicine
Other brands with the same active ingredient
These brands contain the same active ingredient (Esomeprazole). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Bsom 40 is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For oral dosage forms, healing of erosive esophagitis is achieved with 20 mg or 40 mg once daily for 4 to 8 weeks, and most patients heal within that period. For patients who do not heal after 4 to 8 weeks, an additional 4 to 8 weeks of treatment may be considered. Maintenance of healing of erosive esophagitis uses 20 mg once daily, though clinical studies did not extend beyond 6 months. Symptomatic GERD is treated with 20 mg once daily for 4 weeks, and if symptoms do not resolve completely after 4 weeks, an additional 4 weeks of treatment may be considered. For Helicobacter Pylori eradication using triple therapy to reduce the risk of duodenal ulcer recurrence, Esomeprazole 40 mg once daily is given for 10 days together with Amoxicillin 1000 mg twice daily for 10 days and Clarithromycin 500 mg twice daily for 10 days. For Zollinger-Ellison Syndrome, the dose is 20 to 80 mg once daily, adjusted individually, with treatment continued as long as clinically indicated. Acid related dyspepsia is treated with 20 to 40 mg once daily for 2 to 4 weeks according to response. Duodenal ulcer is treated with 20 mg once daily for 2 to 4 weeks. Gastric ulcer is treated with 20 to 40 mg once daily for 4 to 8 weeks. For IV injection or IV infusion in GERD with erosive esophagitis, adult patients aged 18 years and above receive 20 mg or 40 mg once daily, given as an IV injection over more than 3 minutes or as an IV infusion over 10 to 30 minutes. In pediatric patients aged 1 year to 17 years, those with body weight under 55 kg receive 10 mg once daily, and those with body weight of 55 kg or more receive 20 mg once daily. Pediatric patients aged 1 month to under 1 year receive 0.5 mg per kg once daily, given as an IV infusion over 10 to 30 minutes. For risk reduction of rebleeding of gastric or duodenal ulcers following therapeutic endoscopy in adults, adult patients aged 18 years and above receive 80 mg as an IV infusion over 30 minutes, followed by a continuous infusion of 8 mg per hour for a total treatment duration of 72 hours.
Side Effects
The most commonly reported side effects with Esomium include headache, diarrhoea, nausea, flatulence, abdominal pain, constipation and dry mouth. The types of related side effects seen during long term maintenance treatment of up to 12 months are similar to those seen with short term use.
Cautions & Contraindications
Warnings & Precautions
General: A symptomatic response to Esomium therapy does not rule out the presence of gastric malignancy. Information for patients: Esomium capsules should be taken at least one hour before meals. Patients who have difficulty swallowing capsules can add one tablespoon of applesauce to an empty bowl, open the Esomium capsule, and carefully empty the pellets inside onto the applesauce. The pellets should be mixed with the applesauce and swallowed right away. The applesauce used should not be hot, and it should be soft enough to swallow without chewing. The pellets themselves should not be chewed or crushed. The pellet and applesauce mixture should not be stored for later use. Antacids may be used alongside Esomium.
Contraindications
Esomeprazole should not be used in patients who are known to be hypersensitive to any component of the formulation.