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Other brands with the same active ingredient
These brands contain the same active ingredient (Brivaracetam). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Bivara 25 FC is indicated for:
Pharmacology
This is a preparation of Brivaracetam which is an anticonvulsant. The precise mechanism by which Brivaracetam exerts its anticonvulsant activity is not known. Brivaracetam displays a high and selective affinity for synaptic vesicle protein 2A (SV2A) in the brain which may contribute to the anticonvulsant effect.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage Brivaracetam tablet or oral solution is taken in oral route. It may be taken with or without food. The recommended dose for patients 1 month of age and older is included below. In pediatric patients weighing less than 50 kg, the recommended dosing regimen is dependent upon body weight. When initiating treatment, gradual dose escalation is not required. Dose should be adjusted based on clinical response and tolerability.Adults (16 years and older)- Initial dose: 50 mg twice daily (100 mg per day) Minimum and maximum maintenance dose: 25 mg to 100 mg twice daily (50 mg to 200 mg per day) Pediatric patients weighing 50 kg or more- Initial dose: 25 mg to 50 mg twice daily (50 mg to 100 mg per day) Minimum and maximum maintenance dose: 25 mg to 100 mg twice daily (50 mg to 200 mg per day) Pediatric patients weighing 20 kg to less than 50 kg- Initial dose: 0.5 mg/kg to 1 mg/kg twice daily (1 mg/kg to 2 mg/kg per day) Minimum and maximum maintenance dose: 0.5 mg/kg to 2 mg/kg twice daily (1 mg/kg to 4 mg/kg per day) Pediatric patients weighing 11 kg to less than 20 kg- Initial dose: 0.5 mg/kg to 1.25 mg/kg twice daily (1 mg/kg to 2.5 mg/kg per day) Minimum and maximum maintenance dose: 0.5 mg/kg to 2.5 mg/kg twice daily (1 mg/kg to 5 mg/kg per day) Pediatric patients weighing less than 11 kg- Initial dose: 0.75 mg/kg to 1.5 mg/kg twice daily (1.5 mg/kg to 3 mg/kg per day) Minimum and maximum maintenance dose: 0.75 mg/kg to 3 mg/kg twice daily (1.5 mg/kg to 6 mg/kg per day) Geriatric use: Dose selection for an elderly patient should be judicious, usually starting at the low end of the dosing range.Renal impairment: Dose adjustments are not required for patients with impaired renal function. Use of brivaracetam is not recommended in patients with end stage renal disease undergoing dialysis.Use in children and adolescents: Safety and effectiveness in pediatric patients below the age of 1 month have not been established.
Side Effects
The most common side effects are nausea/vomiting, constipation, somnolence and sedation, dizziness, fatigue, cerebellar coordination and balance disturbances and irritability.
Cautions & Contraindications
Warnings & Precautions
Antiepileptic drugs (AEDs), including Bricet, increase the risk of suicidal thoughts or behavior. Patients treated with any AED should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior and/or any unusual changes in mood or behavior. Bricet causes somnolence, fatigue, dizziness and disturbance in coordination. Patients should be monitored for these signs and symptoms and advised not to drive or operate machinery. Bricet causes psychiatric adverse reactions which included both non-psychotic symptoms (irritability, anxiety, nervousness, aggression, belligerence, anger, agitation, restlessness, depression, depressed mood, tearfulness, apathy, mood swings, psychomotor hyperactivity, abnormal behavior and adjustment disorder) and psychotic symptoms (psychotic disorder along with hallucination, paranoia, acute psychosis and psychotic behavior). As with most antiepileptic drugs, Bricet should generally be withdrawn gradually because of the risk of increased seizure frequency and status epilepticus.
Contraindications
Brivaracetam is contraindicated in patients with known hypersensitivity to brivaracetam or any other components of this product.
Pregnancy & Breastfeeding
Pregnancy: Brivaracetam should not be used during pregnancy unless clinically necessary i.e. (if the benefit to the mother clearly outweighs the potential risk to the fetus).Lactation: No data are available regarding the presence of brivaracetam in human milk, the effects on the breastfed infant or the effects of the drug on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for brivaracetam and any potential adverse effects on the breastfed infant from brivaracetam or from the underlying maternal condition.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
The adverse reactions with Brivaracetam overdose are vertigo, balance disorder, fatigue, nausea, diplopia, anxiety and bradycardia. There is no specific antidote for overdose with Brivaracetam. In the event of overdose, standard medical practice for the management of any overdose should be used. An adequate airway, oxygenation and ventilation should be ensured; monitoring of cardiac rate and rhythm and vital signs is recommended.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store in a cool (below 30°C) and dry place protected from light. Keep away from the reach of children.
Drug Interactions
Common questions about Bivara 25 FC 25 mg
What is Bivara 25 FC 25 mg Tablet?
Bivara 25 FC 25 mg Tablet is a medicine that contains Brivaracetam. It is made by Advanced Chemical Industries PLC. It belongs to the Adjunct anti-epileptic drugs group of medicines.
What is Bivara 25 FC used for?
Bivara 25 FC is used for: Epilepsy.
What are the side effects of Bivara 25 FC?
The most common side effects are nausea/vomiting, constipation, somnolence and sedation, dizziness, fatigue, cerebellar coordination and balance disturbances and irritability.
Can I take Bivara 25 FC during pregnancy or while breastfeeding?
Pregnancy: Brivaracetam should not be used during pregnancy unless clinically necessary i.e. (if the benefit to the mother clearly outweighs the potential risk to the fetus).Lactation: No data are available regarding the presence of brivaracetam in human milk, the effects on the breastfed infant or the effects of the drug on milk production. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Bivara 25 FC?
The adverse reactions with Brivaracetam overdose are vertigo, balance disorder, fatigue, nausea, diplopia, anxiety and bradycardia. There is no specific antidote for overdose with Brivaracetam. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Bivara 25 FC?
Store in a cool (below 30°C) and dry place protected from light. Keep away from the reach of children.
Can I take other medicines with Bivara 25 FC?
Some medicines can interact with Brivaracetam, for example: Carbamazepine, Levetiracetam, Phenytoin, Rifampicin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Bivara 25 FC?
Bivara 25 FC is a prescription (Rx) medicine. Take it as your doctor advises.