Biocal Kit
Rx150 mg+600 mg+400 IU • Tablet
Indications & Uses
Biocal Kit is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Day 1 to Day 10: Take one Calcium & Vitamin D3 tablet daily after meal.Day 11: Take one Ibandronic Acid tablet with a full glass of plain water 1 hour before the breakfast in empty stomach. After taking Ibandronic Acid tablet, patient can usually sit or walk around but must not lie down or take any food or liquid (except plain water) for 1 hour.Day 11 to Day 30: Take one Calcium & Vitamin D3 tablet daily after meal.Use in children and adolescents: Safety and effectiveness in pediatric patients have not been established.
Side Effects
Most common side effects are back pain, dyspepsia, pain in extremity, diarrhea, flatulence, constipation, headache, myalgia and upper Gl discomfort.
Cautions & Contraindications
Warnings & Precautions
Ibandronic Acid- Caution should be used when ibandronic acid is given to patients with active upper gastrointestinal problems (such as known Barrett’s esophagus, dysphagia, other esophageal diseases, gastritis, duodenitis or ulcers). Hypocalcemia and other disturbances of bone and mineral metabolism should be treated before starting ibandronic acid therapy. Discontinue ibandronic acid if any patient develop severe bone, joint and muscle pain. If any Patient develops osteonecrosis of the jaw, discontinuation of bisphosphonate therapy should be considered. Any patient presenting with thigh or groin pain should be evaluated to rule out an incomplete femur fracture and interruption of bisphosphonate therapy should be considered. Ibandronic acid is not recommended for use in patients with severe renal impairment (creatinine clearance of <30 ml/min). Calcium & Vitamin D3- Patients with mild to moderate renal failure or mild hypercalciuria should be periodically checked for plasma calcium levels and urinary calcium excretion. Calcium should be used cautiously in patients with pre-existing heart disease, sarcoidosis, kidney stones and kidney diseases. When hypercalcemia occurs, discontinuing of the drug should be considered. Patients with a history of stone formation should increase their fluid intake. Doses of calcium and iron should be separated by several hours
Contraindications
This kit is contraindicated in patients with known hypersensitivity to ibandronic acid or calcium or vitamin D3 or any other components of this product.Ibandronic Acid: It is contraindicated in patients with- Abnormalities of the esophagus which delay esophageal emptying such as stricture or achalasia Inability to stand or sit upright for at least 60 minutes Hypocalcaemia. Calcium & Vitamin D3: The combination is contraindicated in patients with- Hypercalcaemia Hyperparathyroidism Hypercalciuria Nephrolithiasis Severe renal insufficiency Concomitant digoxin therapy Renal calculi Zollinger-Ellison syndrome.