Indications & Uses
Betavate-CL is indicated for:
Pharmacology
Betamethasone + Clotrimazole combines two active ingredients that work in different ways. Clotrimazole is a broad-spectrum antifungal that treats superficial infections caused by dermatophytes, yeasts, and Malassezia furfur. It works by blocking the fungus from producing ergosterol, a key building block of its cell membrane; without it, the membrane becomes unstable and the fungal cell dies. Betamethasone dipropionate is a corticosteroid that helps reduce inflammation, ease itching, and constrict blood vessels, though the precise way corticosteroids achieve these effects is not fully understood.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Sufficient cream should be applied to the affected skin and the surrounding area twice daily, in the morning and evening. Treatment is continued for 2 weeks for tinea cruris and tinea corporis, and for 4 weeks for tinea pedis; it should not be used for longer than four weeks. Safety and effectiveness have not been established in children under 12 years of age.
Side Effects
Adverse reactions reported in clinical trials of this preparation included paresthesia, seen in about 1.9% of patients. Rash, edema and secondary infection were each reported in fewer than 1% of patients. Burning and dry skin were reported in 1.6% of patients, and stinging occurred in fewer than 1% of patients.
Cautions & Contraindications
Contraindications
Contraindications This topical cream should not be used by anyone who is sensitive to any of its ingredients, to other corticosteroids, or to imidazole antifungals. If irritation or a sensitivity reaction develops during use, treatment should be stopped and suitable alternative care given. The cream should also be avoided in facial rosacea, acne vulgaris, perioral dermatitis, perianal and genital itching, nappy (diaper) rash, and bacterial or viral skin infections. When applied to the skin, corticosteroids can be absorbed into the bloodstream, and in some cases this may cause temporary suppression of the body's hypothalamic-pituitary-adrenal (HPA) axis, which regulates natural steroid hormone production. If this occurs, the doctor may advise stopping the cream or using it less often, and the effect usually reverses once treatment is adjusted. Children may be more prone to this kind of systemic effect than adults, since their skin surface area is larger relative to their body weight, meaning proportionally more of the drug can be absorbed.
Pregnancy & Breastfeeding
There is not enough evidence to confirm that this medicine is safe to use during pregnancy. Studies in animals show that clotrimazole does not cause birth defects, though it can harm the developing foetus when taken by mouth in high doses. Applying corticosteroids to the skin has also been shown to cause abnormalities in foetal development in animal studies. For this reason, the cream should only be used during pregnancy if the expected benefit outweighs the possible risk to the unborn baby, and it should not be used generously, meaning not in large amounts and not over long periods. It is not known whether the ingredients in this preparation pass into human breast milk, so it should be used with caution by breastfeeding mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
An acute overdose of Betamethasone + Clotrimazole cream is unlikely, and it wouldn't be expected to put a person's life at risk. Even so, the cream should not be used for longer than the time the doctor has prescribed.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Betamethasone + Clotrimazole below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Common questions about Betavate-CL 100 mg
What is Betavate-CL 100 mg Ointment?
Betavate-CL 100 mg Ointment is a medicine that contains Betamethasone + Clotrimazole. It is made by Drug International Ltd., Gopalpur. It belongs to the Betamethasone & Combined preparations group of medicines.
What is Betavate-CL used for?
Betavate-CL is used for: Fungal Infection.
What are the side effects of Betavate-CL?
Adverse reactions reported in clinical trials of this preparation included paresthesia, seen in about 1.9% of patients. Rash, edema and secondary infection were each reported in fewer than 1% of patients.
Can I take Betavate-CL during pregnancy or while breastfeeding?
There is not enough evidence to confirm that this medicine is safe to use during pregnancy. Studies in animals show that clotrimazole does not cause birth defects, though it can harm the developing foetus when taken by mouth in high doses. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Betavate-CL?
An acute overdose of Betamethasone + Clotrimazole cream is unlikely, and it wouldn't be expected to put a person's life at risk. Even so, the cream should not be used for longer than the time the doctor has prescribed. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Betavate-CL?
Store Betamethasone + Clotrimazole below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Do I need a prescription for Betavate-CL?
Betavate-CL is a prescription (Rx) medicine. Take it as your doctor advises.