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These brands contain the same active ingredient (Sparfloxacin). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Asaf is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The recommended daily dose of Sparfloxacin in patients with normal kidney function starts with two 200 mg tablets on the first day as a loading dose. After that, one 200 mg tablet should be taken every 24 hours, continuing for a total of 10 days of treatment (11 tablets in all). For patients with impaired kidney function (creatinine clearance below 50 mL/min), the recommended daily dose is likewise two 200 mg tablets on the first day as a loading dose. After that, one 200 mg tablet should be taken every 48 hours, for a total of 9 days of treatment (6 tablets in all).
Side Effects
Most of the side effects are mild to moderate in severity and transient in nature. The most frequently reported events with the recommended dosage were: Photosensitivity reaction, Diarrhea, Nausea, Headache, Dyspepsia, Dizziness, Insomnia, Abdominal pain, Pruritus, Taste perversion, QTc interval prolongation, Vomiting, Flatulence, Vasodilatation.
Cautions & Contraindications
Warnings & Precautions
Special warnings: Moderate to severe phototoxic reactions have occurred in patients exposed to direct or indirect sunlight or to artificial ultraviolet light (e.g., sunlamps) during or following treatment. Patients should be advised to discontinue Spark therapy at the first signs or symptoms of a phototoxicity reaction such as: Sensation of skin burning Swelling Rash Itching Dermatitis Increases in the QTc interval. The safety and effectiveness of Spark in children, adolescents (under the age of 18 years), pregnant women, and lactating women have not been established.Precaution- Adequate hydration of patients receiving Spark should be maintained to prevent the formation of a highly concentrated urine. Administer Spark with caution in the presence of renal insufficiency. Avoid the concomitant prescription of medications known to prolong the QTc interval, e.g., erythromycin, terfenadine etc. Excessive exposure to sunlight should be avoided.
Contraindications
Sparfloxacin should not be used by anyone who is hypersensitive to any of its ingredients. It is also contraindicated during pregnancy and lactation, in patients with Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency, and in those with a history of Achilles tendinitis linked to previous fluoroquinolone use.