Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Other brands with the same active ingredient

These brands contain the same active ingredient (Istradefylline). Same strength and form. Confirm the switch with your doctor or pharmacist.

Indications & Uses

Aric 20 is indicated for:

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

The recommended dosage of Istradefylline is 20 mg administered orally once daily. The dosage may be increased to a maximum of 40 mg once daily, based on individual need and tolerability. Patients who smoke 20 or more cigarettes per day (or the equivalent of another tobacco product) the recommended dosage is 40 mg once daily.Patients with Hepatic Impairment: Maximum recommended dosage with moderate hepatic impairment is 20 mg once daily, use of Istradefylline in patients with severe hepatic impairment should be avoided.Use in Children: Safety and effectiveness of Istradefylline in pediatric patients have not been established.

Side Effects

The most common adverse reactions of Aric are dyskinesia, dizziness, constipation, nausea, hallucination, and insomnia.

Cautions & Contraindications

Warnings & Precautions

Monitor patients for dyskinesia or exacerbation of existing dyskinesia. If hallucinations / psychotic behavior / impulse control / compulsive behaviors occurs then consider dosage reduction or stop Aric.

Contraindications

Istradefylline is contraindicated in patients with known hypersensitivity to any component of this drug, and in patients with severe hepatic impairment.

Drug Interactions

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Last updated: 15 Aug 2026