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Other brands with the same active ingredient
These brands contain the same active ingredient (Amitriptyline Hydrochloride). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Amitip 10 is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Depression: The usual starting dose is 75 mg daily (30 to 75 mg daily for elderly patients and adolescents), taken either in divided doses or as a single dose at bedtime. The dose may be increased gradually as needed to 150 to 200 mg daily. Amitriptyline is not recommended for depression in children under 16 years of age. Nocturnal enuresis (bedwetting): Children aged 7 to 10 years: 10 to 20 mg at night. Children aged 11 to 16 years: 25 to 50 mg at night. Treatment, including gradual withdrawal, should not continue for more than 3 months. A full physical examination is required before any further course of treatment. Prevention of migraine: 100 mg daily. Tension headache: 10 to 25 mg three times daily.
Side Effects
Anticholinergic: excessive sweating, dry mouth, blurred vision, very high body temperature, difficulty passing urine and widening of the urinary tract. Cardiovascular reactions: low blood pressure, fainting, postural hypotension, high blood pressure, fast heartbeat, palpitations, myocardial infarction, etc. CNS and neuromuscular: confusional states, poor concentration, disorientation, delusions, etc. Allergic: skin rash, urticaria, photosensitisation, etc. Haematological: bone-marrow depression. Gastrointestinal: nausea, epigastric distress, vomiting, loss of appetite, stomatitis, unpleasant taste, weight loss, diarrhoea, constipation, etc. Endocrine: testicular swelling, gynaecomastia, breast enlargement, galactorrhoea, etc.
Cautions & Contraindications
Warnings & Precautions
Use with caution in patients with a history of epilepsy, glaucoma or raised intra-ocular pressure, urinary retention, heart disease, diabetes, liver impairment, thyroid disease, or psychoses (it may worsen mania), and during pregnancy.
Contraindications
Amitriptyline should not be used in people who have had a myocardial infarction (heart attack), in those with arrhythmias (particularly heart block of any degree), in mania, or in severe liver disease. During the early stages of treatment, sedation may affect the ability to drive or operate machinery.