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Other brands with the same active ingredient
These brands contain the same active ingredient (Epalrestat). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Aldorin is indicated for:
Pharmacology
Epalrestat works by specifically blocking the enzyme aldose reductase, which reduces the buildup of sorbitol in nerve tissue. In people with diabetic peripheral neuropathy, this action helps ease symptoms and improves nerve function.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual adult dose is 1 tablet (50 mg) taken three times a day, before each meal. Your doctor may change the dose depending on your age and how you are responding to the treatment.
Side Effects
Major side effects include liver function abnormalities and a drop in platelet count (thrombocytopenia). If signs of liver trouble appear, the medicine should be stopped right away and suitable treatment given. Other reported effects include general discomfort (malaise), headache, stomach pain, nausea, and allergic reactions.
Cautions & Contraindications
Warnings & Precautions
Epastat may be considered for patients whose glycohemoglobin levels remain high even after standard diabetes management, including diet therapy, exercise therapy, and treatment with an oral hypoglycemic agent or insulin. Its effectiveness has not been established in patients with diabetic peripheral neuropathy involving irreversible organic changes. Patients should be monitored closely while taking Epastat. If no benefit is seen after 12 weeks of treatment, other suitable therapies should be considered.
Contraindications
Epalrestat should not be used by patients who are known to be hypersensitive to it.
Pregnancy & Breastfeeding
Epalrestat has not been proven safe in pregnant women. It may be given to a pregnant woman, or to a woman who could be pregnant, only when the expected benefit of the treatment is greater than the possible risks. Women should avoid breastfeeding while they are taking epalrestat.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Do not store above 30°C temperature. Keep away from light and wet place. Keep out of reach of children.
Common questions about Aldorin 50 mg
What is Aldorin 50 mg Tablet?
Aldorin 50 mg Tablet is a medicine that contains Epalrestat. It is made by Eskayef Pharmaceuticals Ltd. Chandana, Gazipur. It belongs to the Aldose reductase inhibitor group of medicines.
What is Aldorin used for?
Aldorin is used for: Pain.
What are the side effects of Aldorin?
Major side effects include liver function abnormalities and a drop in platelet count (thrombocytopenia). If signs of liver trouble appear, the medicine should be stopped right away and suitable treatment given.
Can I take Aldorin during pregnancy or while breastfeeding?
Epalrestat has not been proven safe in pregnant women. It may be given to a pregnant woman, or to a woman who could be pregnant, only when the expected benefit of the treatment is greater than the possible risks. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Aldorin?
Do not store above 30°C temperature. Keep away from light and wet place.
Do I need a prescription for Aldorin?
Aldorin is a prescription (Rx) medicine. Take it as your doctor advises.