ওষুধের পারস্পরিক ক্রিয়া যাচাই

Antacids: Concomitant administration of high doses of antacids (sodium bicarbonate and aluminium hydroxide) or H 2 blockers reduce peak plasma level by 24% to 42% and the extent of absorption by 27% to 32%, respectively.Probenecid: Renal excretion of cefpodoxime was inhibited by probenecid and resulted in an approximately 31% increase in AUC.Nephrotoxic drugs: Close monitoring of renal function is advised when Xepodox is administered concomitantly with compounds of known nephrotoxic potential.

Concomitant administration of Cefpodoxime at high doses with antacids or H2 blockers reduces peak plasma levels of Cefpodoxime.