ইঙ্গিত
Torsem is indicated for the management of oedema of cardiac, renal and hepatic origin. It is also indicated for the management of hypertension, either as a sole therapeutic agent or in combination with other classes of antihypertensive agents.
⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।
ফার্মাকোলজি
Torasemide blocks the Na+/K+/2Cl- carrier system by interfering with the chloride binding site in the lumen of the thick ascending limb of the loop of Henle, which reduces reabsorption of sodium and chloride. This speeds up the delivery of tubular fluid and electrolytes to the distal sites where hydrogen and potassium ions are secreted, while the resulting contraction of plasma volume raises aldosterone production. The greater fluid delivery combined with high aldosterone levels promotes sodium reabsorption at the distal tubules, and because more sodium reaches the distal renal tubule, torasemide indirectly boosts potassium excretion through the sodium-potassium exchange mechanism. No effects of torasemide have been shown in other segments of the nephron. In this way, torasemide raises urinary excretion of sodium, chloride, and water without meaningfully changing glomerular filtration rate, renal plasma flow, or acid-base balance. Its blood-pressure-lowering effect comes from this diuretic action: by lowering extracellular and plasma fluid volume, it temporarily reduces blood pressure and also decreases cardiac output.
Pregnancy & Breastfeeding
Pregnancy: There have been no adequate, well-controlled studies of torasemide in pregnant women, and animal studies do not reliably predict how a drug will behave in humans. For this reason, torasemide should be used during pregnancy only when clearly needed.
Breastfeeding: It is not known whether torasemide passes into human breast milk. Since many drugs do pass into breast milk, it should be used with caution in a nursing mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
ডোজ নির্দেশিকা
⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।