Community data Updated 2 মাস আগে

Tetracycline Hydrochloride

Tetracycline group of drugs Prescription

ইঙ্গিত

Fever Peptic Ulcer Helicobacter Pylori Infection Amoebiasis Acne Vulgaris Conjunctivitis

Tetracillin is a broad-spectrum antibiotic. It is highly effective in treating infections caused by Borrelia recurrentis (relapsing fever), Calymmatobacterium granulomatis (granuloma inguinale), Chlamydia species (psittacosis, lymphogranuloma venereum, trachoma, inclusion conjunctivitis), Francilsella tularensis (tularaemia), Haemophilus ducreyi (chancroid), Leptospira (meningitis, jaundice), Mycoplasma pneumoniae (non-gonococcal urethritis), Pseudomonas mallei (glanders and melioidosis), Rickettsiae (typhus fever, Q-fever, Rocky Mountain spotted fever) and Vibrio species (cholera). It is also highly effective, alone or in combination with streptomycin, in treating infections due to Brucella species (brucellosis), plague and severe acne vulgaris. In acute intestinal amoebiasis, Tetracillin is a useful adjunct to amoebicides. Tetracillin is indicated in pneumonia, tetanus, gas gangrene and dysentery, and as second- or third-line therapy in gonorrhoea and syphilis. It is also used as adjunct therapy with bismuth subcitrate and metronidazole to eradicate H. pylori in the treatment of gastric and duodenal ulcers.

⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।

ফার্মাকোলজি

Tetracycline is a broad-spectrum antibiotic that stops the growth of many bacteria as well as rickettsiae, chlamydia, mycoplasma, and brucella. It works by blocking protein synthesis in these organisms. Taken as a single oral dose, it reaches its peak level in the blood within 2 to 4 hours, and its half-life ranges from 6 to 9 hours. Because it undergoes enterohepatic circulation, Tetracycline can remain detectable in the blood for some time even after treatment has stopped.

Pregnancy & Breastfeeding

During pregnancy, tetracycline crosses the placenta, is found in foetal tissues and has an embryotoxic effect. For this reason, it should not be used in pregnancy unless considered essential, in which case the maximum daily dose should be 1 gm. Tetracycline has also been found in human milk, and its use during breastfeeding may cause permanent tooth discoloration in the developing infant; enamel hypoplasia has also been reported.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

ডোজ নির্দেশিকা

⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।

Adults: Usual adult dosage is 250 mg or 500 mg every 6 hours by mouth, preferably taken 1 hour before or 2 hours after a meal. Higher doses of up to 3 or 4 gm daily have occasionally been given in resistant infections. Specific dosage recommendations are as follows. Brucellosis: 500 mg every 6 hours for 3 weeks. Chlamydial infections: 500 mg every 6 hours for at least 2 weeks. Non-specific urethritis: 500 mg every 6 hours for 7 days. Severe acne: 1 gm per day for 2 to 3 weeks, followed by 1 capsule daily for 3 to 4 months. Gonorrhoea: an initial oral dose of 1.5 gm, followed by 500 mg every 6 hours for 4 days; the total dose should be 9 gm. Syphilis: 500 mg every 6 hours for 15 days, but therapy should be continued for 30 days if the disease has been present for longer than 1 year. Endocervical infections: 500 mg every 6 hours for 7 days. Children over 12 years of age: 25 to 50 mg/kg divided into 2 or 4 equal doses. The maximum dose should not exceed the recommended adult dose. Children below 12 years of age: not recommended. Administration: Tetracycline should be taken orally, an hour before or two hours after a meal, and therapy should be continued for up to three days after the characteristic symptoms of the infection have subsided. It should be used with caution in the treatment of elderly patients, in whom accumulation is a possibility.

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