ইঙ্গিত
Soritene 0.1% cream is applied to the skin to treat plaque psoriasis. It is also used to treat acne.
⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।
ফার্মাকোলজি
Topical tazarotene works by blocking ornithine decarboxylase (ODC), an enzyme linked to cell proliferation and hyperplasia. It also suppresses MRP8, a marker of inflammation found at high levels in the epidermis of people with psoriasis. In studies on human keratinocyte cultures, the drug inhibits formation of the cornified envelope, whose build-up contributes to psoriatic scale. Tazarotene further induces expression of a gene that may act as a growth suppressor in human keratinocytes, potentially helping to curb epidermal hyperproliferation within treated plaques.
Pregnancy & Breastfeeding
There are no adequate and well-controlled studies of Tazarotene in pregnant women. When used only on the face for acne, systemic absorption may be lower because less surface area is treated, but Tazarotene is still a teratogenic substance, and the level of exposure needed to cause harm in humans is not known. It is also not known whether this drug passes into human breast milk, so caution should be exercised when Tazarotene is given to a nursing woman.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
ডোজ নির্দেশিকা
⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।