ইঙ্গিত
Pamulin ointment is indicated for use in adults and pediatric patients aged 9 months and older for the topical treatment of impetigo (up to 100 cm 2 in total area in adults or 2% total body surface area in pediatric patients aged 9 months or older) due to Staphylococcus aureus (methicillin-susceptible ... Read morePamulin ointment is indicated for use in adults and pediatric patients aged 9 months and older for the topical treatment of impetigo (up to 100 cm 2 in total area in adults or 2% total body surface area in pediatric patients aged 9 months or older) due to Staphylococcus aureus (methicillin-susceptible isolates only) or Streptococcus pyogenes. Safety in patients younger than 9 months has not been established. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Pamulin and other antibacterial drugs, Pamulin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.
⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।
ফার্মাকোলজি
Retapamulin works by selectively blocking bacterial protein synthesis, attaching to a distinct site on the 50S subunit of the bacterial ribosome through a mechanism unlike that of other antibiotics. This binding site involves ribosomal protein L3 and lies within the region of the ribosomal P-site and peptidyl transferase center. By attaching here, pleuromutilins such as retapamulin block peptidyl transfer, interfere with P-site interactions, and stop the normal assembly of functional 50S ribosomal subunits. Against Staphylococcus aureus and Streptococcus pyogenes, retapamulin acts as a bacteriostatic agent at its in vitro minimum inhibitory concentration (MIC) for these organisms.
Pregnancy & Breastfeeding
Pregnancy Category B. It is not known whether retapamulin passes into breast milk. Since many medicines do pass into breast milk, it should be used with caution in women who are breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
ডোজ নির্দেশিকা
⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।