Prochlorperazine Maleate

Adults: Antiemetic use in children (not recommended for children weighing under 10 kg or younger than 2 years): for 10 to 14 kg, give 2.5 mg every 12 to 24 hours as needed, up to a maximum of 7.5 mg per day. For 15 to 18 kg, give 2.5 mg every 8 to 12 hours as needed, up to a maximum of 10 mg per day. For 19 to 39 kg, give 2.5 mg every 8 hours or 5 mg every 12 hours as needed, up to a maximum of 15 mg per day. Adults: 5 to 10 mg, 3 to 4 times a day, with a usual maximum of 40 mg per day. Antipsychotic use in children (not recommended for children weighing under 10 kg or younger than 2 years): for children aged 2 to 12 years, give 2.5 mg 2 to 3 times a day, increasing the dose as needed up to a maximum daily dose of 20 mg for ages 2 to 5 years and 25 mg for ages 6 to 12 years. Adults: 5 to 10 mg, 3 to 4 times a day; doses of up to 150 mg per day may be needed in some patients for treatment of severe disturbances. Nonpsychotic anxiety in adults: the usual dose is 15 to 20 mg per day in divided doses; doses above 20 mg per day, or use for longer than 12 weeks, should not be given. Elderly patients: start with 2.5 to 5 mg, 1 to 2 times a day, increasing the dose at intervals of 4 to 7 days by 2.5 to 5 mg per day, and adjusting the dosing frequency (twice daily, three times daily, and so on) as needed to control response or side effects; the maximum daily dose should probably not exceed 75 mg in elderly patients, and gradual increases in dose may help prevent side effects or reduce their severity. Prochlorperazine may be taken with or without food.