ইঙ্গিত
ফার্মাকোলজি
Pizotifen reduces the peripheral effects of serotonin and histamine, both of which increase the permeability of cranial blood vessel membranes and the leakage of plasmakinin, and this action helps shift pain thresholds during a migraine. It also blocks 5-HT receptors, which lessens serotonin's role in constricting cranial blood vessels and its tendency to boost platelet activity and clumping. Some evidence suggests the drug curbs the peripheral effects of bradykinin as well. Pizotifen may also limit how much serotonin blood platelets reabsorb, a change that affects vessel tone and reduces the passive widening of extracranial arteries. As for its tendency to stimulate appetite, this is thought to arise from its influence on metabolism rather than any direct action on the brain's appetite centre.
Pregnancy & Breastfeeding
Pizotifen hasn't been studied extensively in pregnant women, though no harmful effects have come to light so far. Given this limited data, it should only be used during pregnancy if the expected benefit to the mother outweighs any possible risk to the unborn baby. Similarly, its safety while breastfeeding hasn't been established, so it's best avoided by nursing mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
ডোজ নির্দেশিকা
⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।