Mebendazole

Mebendazole is a synthetic, broad-spectrum anthelmintic effective against most nematodes and several other worm species. It is mainly used to treat intestinal nematode infections. It works by blocking the formation of microtubules within the worms and depleting their glucose stores, which the worms need to survive.

When taken by mouth, only about 2-10% of the dose is absorbed from the gut, with blood levels peaking anywhere between 30 minutes and 7 hours after intake. Once absorbed, mebendazole binds extensively to plasma proteins, and it is cleared from the body with a half-life of roughly 2.8 to 9 hours.