শুধুমাত্র তথ্যমূলক — চিকিৎসা পরামর্শ নয়। সর্বদা লাইসেন্সপ্রাপ্ত স্বাস্থ্যসেবা প্রদানকারীর পরামর্শ নিন।

MedBD
EN
Community data Updated 2 মাস আগে

ইঙ্গিত

Ilodon is an atypical antipsychotic indicated for the treatment of schizophrenia in adults, and for the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults.

⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।

ফার্মাকোলজি

Iloperidone shows high affinity and maximal receptor occupancy for dopamine D2 receptors in the caudate nucleus and putamen of the brains of schizophrenic patients. The improvement in cognition is attributed to iloperidone's high affinity for α adrenergic receptors. Iloperidone also binds with high affinity to serotonin 5-HT2a and dopamine 3 receptors. Iloperidone binds with moderate affinity to dopamine D4, serotonin 5-HT6 and 5-HT7, and norepinephrine NEα1 receptors. Furthermore, iloperidone binds with weak affinity to serotonin 5-HT1A, dopamine D1, and histamine H1 receptors.

Pregnancy & Breastfeeding

Pregnancy: Exposure during the third trimester may cause extrapyramidal and/or withdrawal symptoms in the newborn.

Lactation: It is not known whether iloperidone or its metabolites pass into human breast milk, nor is it known what effect this may have on a breastfed child or on milk production. Iloperidone has been found to pass into the milk of rats.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

ডোজ নির্দেশিকা

⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।

Adults: Iloperidone must be titrated slowly to avoid orthostatic hypotension. Because of this need to titrate slowly, control of symptoms may be delayed during the first 1 to 2 weeks of treatment. Administer Iloperidone orally twice daily, without regard to meals, and titrate the dosage to avoid orthostatic hypotension. For schizophrenia, the starting dosage is 1 mg twice daily and the recommended dosage is 6 mg to 12 mg twice daily. For bipolar mania, the starting dosage is 1 mg twice daily and the recommended dosage is 12 mg twice daily. In children and adolescents, safety and effectiveness have not been established. Iloperidone is not recommended for patients with severe hepatic impairment.