ইঙ্গিত
Naurif Injection is used to prevent nausea and vomiting caused by cancer chemotherapy (including high-dose cisplatin regimens), both for the first course of treatment and repeat courses. It is also used to prevent and treat nausea and vomiting following surgery. Naurif Tablet is used to prevent nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose cisplatin, as well as nausea and vomiting caused by radiation therapy, including total body irradiation and fractionated abdominal radiation.
⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।
ফার্মাকোলজি
Granisetron is a potent, selective antagonist of 5-HT3 receptors. It produces its antiemetic effect by blocking 5-HT3 receptors both centrally, in the medullary chemoreceptor zone, and peripherally, in the GI tract. Blocking these receptors in turn suppresses visceral afferent stimulation of the vomiting center, likely indirectly at the level of the area postrema, as well as through direct inhibition of serotonin activity within the area postrema and the chemoreceptor trigger zone.
Pregnancy & Breastfeeding
Pregnancy category B. Studies in animals have shown no evidence of impaired fertility or harm to the fetus. Even so, this medicine should be used during pregnancy only if clearly needed. It is not known whether granisetron passes into human breast milk, so caution should be exercised when giving it to a nursing mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
ডোজ নির্দেশিকা
⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।