ইঙ্গিত
Ganrux ophthalmic gel is a topical antiviral for the eye, used to treat acute herpetic keratitis (dendritic ulcers).
⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।
ফার্মাকোলজি
Ganciclovir is the active ingredient in this eye gel. It is a guanosine analogue, and once it is phosphorylated inside the cell, it blocks DNA replication in herpes simplex viruses (HSV).
Both viral and cellular thymidine kinases (TK) convert ganciclovir into ganciclovir triphosphate, its active form. This form fights the virus by stopping viral DNA synthesis in two ways: it competitively inhibits viral DNA polymerase, and it is incorporated directly into the growing viral DNA strand, which halts the chain and prevents the DNA from replicating further.
Pregnancy & Breastfeeding
Pregnancy Category C. In animal studies, ganciclovir given intravenously proved embryotoxic in rabbits and mice, and teratogenic in rabbits. Fetal resorption occurred in at least 85% of rabbits and mice given 60 mg/kg/day and 108 mg/kg/day, respectively (roughly 10,000 and 17,000 times the human ocular dose of 6.25 mcg/kg/day, assuming complete absorption).
Nursing Mothers: Whether topical ophthalmic ganciclovir is absorbed into the bloodstream in amounts sufficient to appear in breast milk is not known. Caution should be exercised when it is given to nursing mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
ডোজ নির্দেশিকা
⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।
পার্শ্বপ্রতিক্রিয়া ও পারস্পরিক ক্রিয়া
পার্শ্বপ্রতিক্রিয়া
No side-effect data recorded yet.