শুধুমাত্র তথ্যমূলক — চিকিৎসা পরামর্শ নয়। সর্বদা লাইসেন্সপ্রাপ্ত স্বাস্থ্যসেবা প্রদানকারীর পরামর্শ নিন।

MedBD
EN
Community data Updated 2 মাস আগে

Dexamethasone + Tobramycin

Aminoglycosides Prescription
🌐 View in English

ইঙ্গিত

T-Dex is used for steroid-responsive inflammatory conditions of the eye (affecting the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe) where a superficial bacterial eye infection is also present. It is also used for chronic anterior uveitis and for corneal injury caused by chemical, radiation or thermal burns, or by penetrating foreign bodies. A combination product containing an anti-infective component is appropriate when the risk of superficial eye infection is high.

⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।

ফার্মাকোলজি

Like other aminoglycosides, Tobramycin exerts its bactericidal effect by specifically blocking normal protein synthesis in susceptible bacteria, although the exact mechanism is still not fully understood. It is believed that this inhibition occurs through an action on the ribosome, causing bacteria to misread messenger RNA. Dexamethasone, for its part, works by inhibiting phospholipase A2, the first step in prostaglandin synthesis, and also suppresses the chemotactic infiltration of neutrophils into the site of inflammation. As a result, its anti-inflammatory activity is about 25 times greater, and its overall therapeutic effectiveness 8 to 10 times greater, than that of hydrocortisone.

Pregnancy & Breastfeeding

Pregnancy: Well-controlled studies in pregnant women have not been conducted. This ophthalmic solution should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus. Nursing Mothers: It is not known whether topical corticosteroids are absorbed into the bloodstream in amounts sufficient to appear in human breast milk. Because many drugs do pass into human milk, nursing mothers should use caution if this ophthalmic solution is prescribed for them.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

ডোজ নির্দেশিকা

⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।

Adults: Eye Drops: Place 1 drop into the conjunctival sac 3 to 5 times a day. During the first 24 to 48 hours, the dose may be raised to 1 drop every 2 hours. Eye Ointment: Apply a small amount into the conjunctival sac 3 to 4 times a day. Close the eyes slowly without blinking and keep them closed for 1 to 2 minutes. Pediatric Use: Safety and effectiveness in pediatric patients under 2 years of age have not been established.