Community data Updated 2 মাস আগে

Darifenacin

BPH/ Urinary retention/ Urinary incontinence Prescription

ইঙ্গিত

Darifen ER is used to treat overactive bladder, helping relieve symptoms such as urgent, frequent, and sometimes uncontrollable urges to urinate.

⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।

ফার্মাকোলজি

Darifenacin is a potent, competitive muscarinic receptor antagonist that binds preferentially to the M3 subtype. M3 receptors govern contraction of the bladder's detrusor muscle, along with GI smooth muscle activity, saliva production, and iris sphincter function. By acting on these receptors, darifenacin can raise the volume threshold that triggers involuntary detrusor contractions, thereby increasing the bladder's effective capacity.

Pregnancy & Breastfeeding

Pregnancy Category C. Darifenacin should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus.

Lactation: It is not known whether Darifenacin passes into human breast milk, so caution should be exercised before giving Darifenacin to a breastfeeding woman.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

ডোজ নির্দেশিকা

⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।

Adults: Darifenacin 7.5 mg once daily; the dose may be increased to 15 mg once daily if the response is not adequate after 2 weeks of therapy. Darifenacin should be taken with liquid. It can be taken with or without food, and should be swallowed whole rather than chewed, divided or crushed. For patients with moderate hepatic impairment, or when co-administered with potent CYP3A4 inhibitors such as ketoconazole, itraconazole, ritonavir, nelfinavir, clarithromycin and nefazodone, the daily dose of Darifenacin should not exceed 7.5 mg.

পার্শ্বপ্রতিক্রিয়া ও পারস্পরিক ক্রিয়া

পার্শ্বপ্রতিক্রিয়া

No side-effect data recorded yet.

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