ইঙ্গিত
Acnesone is used to treat acne vulgaris on the skin's surface in patients aged 12 years and older.
⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।
ফার্মাকোলজি
Dapsone combines anti-inflammatory and antimicrobial effects, and it's likely this dual action that gives it a role in treating acne. On the anti-inflammatory side, it inhibits the neutrophil enzyme myeloperoxidase and eosinophil peroxidase, curbs the production of hypochlorous acid, mops up reactive oxygen species, dampens neutrophil activity, and blocks the signaling triggered by chemoattractants. Its antimicrobial action works much like that of sulfones and sulfonamides: it inhibits bacterial dihydropteroate synthase, an enzyme in the folic acid synthesis pathway, making it effective against organisms that must produce their own folic acid to survive. Laboratory (in vitro) testing has also shown dapsone to have some activity against Propionibacterium species, including Propionibacterium acnes (P. acnes).
Pregnancy & Breastfeeding
Pregnancy Category C. There are no adequate and well controlled studies in pregnant women. Dapsone has been shown to have an embryocidal effect in rats and rabbits. These effects were probably secondary to maternal toxicity. Dapsone Gel should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Although systemic absorption of dapsone following topical application Dapsone Gel is minimal relative to oral dapsone administration, it is known that dapsone is excreted in human milk. Because of the potential for oral dapsone to cause adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue Dapsone Gel, taking into account the importance of the drug to the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
ডোজ নির্দেশিকা
⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।
পার্শ্বপ্রতিক্রিয়া ও পারস্পরিক ক্রিয়া
পার্শ্বপ্রতিক্রিয়া
No side-effect data recorded yet.